Searchable abstracts of presentations at key conferences in endocrinology

ea0035p137 | Calcium and Vitamin D metabolism | ECE2014

Effects of nutritional intervention program on vitamin D serum levels in adolecents

Pastor M Mar Campos , Pardo Ma Dolores Serrano , Soto Ma Luisa Fernandez , de Dios Luna del Castillo Juan , Gomez-Villalba Fernando Escobar , Escobar-Jimenez Fernando

Introduction: Vitamin D deficiency and insufficiency is highly prevalent even in young people. Vitamin D status has been linked to the BMI and insulin resistance.Aim: Determine 25(OH)D concentrations in adolescents before and after nutritional intervention program (NIP) and its relationship to BMI and metabolic syndrome (MS).Methods: We selected 256 secondary school students (127 males) aged between 12 and 16 years from Granada (Sp...

ea0032p1109 | Thyroid cancer | ECE2013

Predictive value of preablation stimulated thyroglobulin in differentiated thyroid cancer

Sanchez Inmaculada Prior , Moreno Ma Angeles Galvez , Jimenez Carmen Tenorio , Exposito Ma Rosa Alhambra , Ortega Raul Ruiz , Ortega Estefania Moreno , Vallejo Casas Juan Antonio , Lopez Pedro Benito

Background: Previous studies have suggested that serum thyroglobulin (Tg) levels at the time of 131I remnant ablation just after thyroidectomy, could be a prognostic tumor marker in differentiated thyroid cancer (DTC).Objective: The aim of this study was to evaluate if serum preablation Tg in the earliest postoperative period could be useful for predicting persistence or recurrence of disease.Methods: This study was a retrospective...

ea0032p1123 | Thyroid cancer | ECE2013

Histopathologic characterization of differentiated thyroid carcinoma in an area of Basque country

Vicente Ma Angeles Vicente , Polo Pilar Sierra , Gomez Carmen Cabrejas , Iregi IzasKun Olaizola , Cabrera Natalia Gonzalez , Gomez Clara Rosario Fuentes , Miguel Ma Angeles Anton

Background: The most common type of thyroid cancer is the well-differentiated thyroid carcinoma (DTC) and that includes papillary (PTC) and follicular carcinoma (FTC). The PTC would represent 50–90% and the FTC over 15–30%. Within the PTC, the most frequent is the classical variant (over 80%), followed by follicular variant (10%) and the rest of variants (<10%). Furthermore, there are differences between PTC and FTC in age at diagnosis, local extension, multicent...

ea0020p588 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Quality of life (QoL) in patients with Cushing's syndrome in a Spanish population: new experience with the CushingQoL questionnaire

Alicia Santos , Eugenia Resmini , Jose Barahona Ma , Camelia Marti , Cheryl Farkas , Olga Roig , Ma Antonia Martinez , Nuria Sucunza , Xavier Badia , Susan M Webb

Quality of life is impaired in patients who have suffered Cushing’s syndrome (CS).Aim: Evaluate QoL with the new questionnaire CushingQoL in Spanish patients in a clinical practice setting and compare it with a generic QoL questionnaire, EuroQoL-5 Dimensions (5D) and its Visual Analogue Scale (VAS).Patients and methods: Forty-three patients with CS (38 pituitary-dependent, 28 cured) were approached during their regular endocri...

ea0081p33 | Calcium and Bone | ECE2022

Psychometric evaluation of the hypoparathyroidism symptom diary using data from two clinical trials

Nelson Lauren , Ing Steven , Rubin Mishaela , Ma Jia , Martin Susan , Sen Rohini , Ayodele Olulade

The Hypoparathyroidism Symptom Diary (HypoPT-SD) was developed for the daily assessment of key symptoms and impact of HypoPT as reported by patients with chronic HypoPT and includes 13-items: a 7-item Symptom subscale, 4-item Impact subscale, and single-item anxiety and depression scores. The current analysis was undertaken to confirm test-retest reliability and construct validity of HypoPT SD Symptom subscale scores using data collected during two open-label, single-arm studi...

ea0081p453 | Reproductive and Developmental Endocrinology | ECE2022

Crosstalk between androgen-ZIP9 signalling and key regulators of mitochondrial dynamics in rodent leydig cells

Brzoskwinia Małgorzata , Kamińska Alicja , Lustofin Sylwia , Hejmej Anna , Bilińska Barbara

Androgen signalling plays a central role in the regulation of male reproduction. Androgens act predominantly by activating the classical intracellular androgen receptor (AR). In addition, alternative pathways may account for rapid effects of androgens via cytoplasmic or membrane-localized androgen receptor − ZIP9. In the testis, the main source of androgens, in particular testosterone, are Leydig cells. The proper synthesis of testosterone depends on the structural condi...

ea0081ep1208 | Late Breaking | ECE2022

Biological profile of patients with Graves’ disease after treatment with iodine 131: experience of the nuclear medicine department of Tlemcen hospital

Nour El Houda Khelil , Mohammed Meghelli Sidi , Zohra Benmansour Fate ma , Nassima Bouhadjer

Hyperthyroidism is a clinical situation characterized by an excess of thyroid hormones in the circulation, the most common etiology of which is Graves’ disease. Its treatment is based on ATS, iodine 131 and surgery. The iratherapy, object of our study, is a treatment of current practice. It is a simple and radical treatment whose goal is to switch to euthyroidism or hypothyroidism. In case of failure or recurrence, a 2nd or even a 3rd cure is prescribed. We conducted a re...

ea0063p626 | Interdisciplinary Endocrinology 1 | ECE2019

Autoimmune thyroiditis (AIT) and diet – the patients’ and medical professionals’ view

Trofimiuk-Muldner Małgorzata , Czubek Ewa , Sztorc Jan , Skalniak Anna , Hubalewska-Dydejczyk Alicja

An increasing interest in improving the quality of life of patients with autoimmune thyroid disorders has been noted during recent years. Although there is little scientific evidence, many patient-oriented publications, websites and support groups recommend changes in diet as well as nutritional supplement use as a cure for thyroid disease and the mean for ailments reduction. The presented survey aimed to explore the patients’ and medical professionals’ approach to n...

ea0049ep1 | Adrenal cortex (to include Cushing's) | ECE2017

Confirmatory tests for diagnosis of primary aldosteronism among Chinese hypertensives

Jiang Minchun , Ma Dujuan , Lin Hailun , Lin Ying , Deng Yajuan , Tang Juying , Zhang Shaoling , Guo Ying

Objective: Primary aldosteronism (PA) has emerged as the most frequent form of secondary hypertension. For the diagnosis of PA, confirmatory testing is indispensable and different tests are recommended by guidelines, including captopril challenge test (CCT) and saline infusion test (SIT). However, there are sparse studies evaluating and comparing CCT and SIT in Chinese population. Hence, we investigate the diagnostic efficiency of CCT and SIT for PA in Chinese hypertensives in...

ea0049ep1127 | Female Reproduction | ECE2017

Relationship between steroid hormones and metabolic profile in women with polycystic ovary syndrome

Lazurova Zora , Figurova Jana , Ujhazi Simona , Mašlankova Jana , Toporcerova Silvia , Lazurova Ivica

Background: There is evidence that polycystic ovary syndrome (PCOS) is commonly associated with higher cardiometabolic risk. Aim of the study was to compare various sex streoids in PCOS women with overweight or obesity (BMI >27) and those with lower BMI. Second aim of the study was to determine the relationship of various sexual setroids to cardiovascular risk in PCOS women.Subjects and methods: Study included 64 Caucasian women with PCOS. F...