Searchable abstracts of presentations at key conferences in endocrinology

ea0032p426 | Diabetes | ECE2013

Early on evaluation of hearing function with transient evoked otoacoustic emissions (TEOAE) and distortion product otoacoustic emissions (DPOAE) in type 2 diabetic patients without hypertension

Dikbas Oguz , Apuhan Tayfun , Altunrende Burcu , Erdurmus Mesut , Tosun Mehmet , Ozturk Serkan

Objective: Altered hearing function in diabetic patients has been found in both pure tone audiometry and otoacoustic emissions (OAEs). We intended to evaluate the cochlear function with both DPOAE and TEOAE in patients with DM without polyneuropathy and hypertension.Patients and methods: Study group consisted of type 2 diabetic patients and healthy control group consisted of healthy age and sex matched volunteers. Detailed ear examination, pure tone audi...

ea0032p446 | Diabetes | ECE2013

Comparison of Irbesartan and combination with Nigella sativa oil in experimental diabetic nephropathy

Peynirci Hande , Sen Saniye , Kanter Mehmet , Ustundag Sedat , Aktas Cevat , Asker Semra

Introduction: Diabetic nephropathy is the leading cause of chronic renal failure worldwide. Related to the increased glucose and its metabolites, activation of renin–angiotensin–aldosterone system, and increased oxidative stress are important in renal deterioration. The studies indicate that suppression of renin–angiotensin–aldosterone system slow down diabetic nephropathy; Nigella sativa decreases blood glucose and oxidative stress. Were viewed th...

ea0032p848 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Advanced glycation end product associated skin autofluorescence and serum corboxymethyl lysine levels in acromegaly

Yavuz Dilek Gogas , Yalin Serap , Yazici Dilek , Yasar Mehmet , Deyneli Oguzhan

Aim: Nonenzymatic advanced glycation and oxidation end-products, advanced glycation end-products (AGEs), impart a potent impact on vessels in diabetic state and in euglycaemic conditions with increased oxidative stress.The aim of this study is to measure AGEs and its relationship with carotid intimae media thickness (CIMT) in acromegaly patients.Method: A case–control study was performed in 225 acromegalic patients (F/M: 116/1...

ea0032p1020 | Thyroid (non-cancer) | ECE2013

Insulin resistance in patients with hypothyroidism or hyperthyroidism without hepatosteatosis

Keskek Sakir Ozgur , Kirim Sinan , Tasdemir Mehmet , Tuzun Dilek , Ortoglu Gulay , Saler Tayyibe

Introduction: Insulin resistance, refers to decreased response of tissues to insulin, primarily associated with type 2 diabetes and glucose intolerance. Several results were obtained in previous studies about the relation between insulin resistance and thyroid dysfunction. In these studies hepatosteatosis was not an exclusion criteria despite insulin resistance has a key role in the development of it. In this study we aimed to investigate insulin resistance in patients with hy...

ea0029p1680 | Thyroid (non-cancer) | ICEECE2012

The role of color-flow Doppler ultrasonography for differential diagnosis between gestational transient thyrotoxicosis and Graves' disease

Zuhur Sayid Shafi , Ozel Alper , Bugdaci Mehmet Sait , Cil Esra , Altuntas Yuksel

Introduction: The differential diagnosis between Graves’ disease (GD) and gestational transient thyrotoxicosis (GTT) is difficult in the absence of history and clinical features of GD. In this study, we aimed to determine the role of peak systolic (PSV) and end-diastolic velocities (EDV) of the right and left inferior thyroid arteries (ITA) as measured by color-flow Doppler ultrasonography (CFDUSG) for discriminating GTT from treatment naive GD.Meth...

ea0026p201 | Pituitary | ECE2011

Evaluation of aortic stiffness in the acromegaly patients with remission

Karatay Eylem , Cakal Erman , Gonulalan Gulsum , Dogan Mehmet , Bozkurt Nujen Colak , Ozbek Mustafa , Delibasi Tuncay

Objective: Cardiovascular diseases (CVD) are the most important cause of mortality in acromegaly patients. Noninvasive assessment of aortic stiffness which can be used as an predictor of atherosclerosis, may be of benefit in acromegaly patients for early diagnosis of CVD. We evaluated the aortic elasticity parameters of acromegalic patients in remission and compared with healthy controls.Methods and results: Study subjects consisted of 20 patients with a...

ea0026p438 | Thyroid (non cancer) | ECE2011

An unusual organ involvement in Werner syndrome: thyroid atrophy

Altay Mustafa , Colbay Mehmet , Toruner Fusun Balos , Akturk Mujde , Sancar Erkam , Cakir Nuri , Arslan Metin

Introduction: Werner syndrome (WS) is an autosomal recessive disease characterized by premature aging, skin changes, gray hair, alopecia, muscle atrophy, osteoporosis, and cataracts and has a high frequency of association with rare neoplasms. In addition, some endocrinological abnormalities were manifested in this rare disease, such as hypogonadism, diabetes mellitus, hyperlipidemia. Atrophic changes of organs and systems such as skin, brain and genital organs were reported. H...

ea0026p446 | Thyroid (non cancer) | ECE2011

Vitamin D levels are associated with serum TSH levels but not with thyroid autoantibodies

Colbay Mehmet , Altay Mustafa , Akturk Mujde , Cakir Nuri , Yetkin Ilhan , Arslan Metin

Introduction: Hashimoto’s thyroiditis (HT) is common autoimmune thyroid disorder and is predominantly the clinical expression of cell-mediated immunity leading to destruction of thyroid cells. Vitamin D plays a role in the regulation of immunity and cell proliferation. So, do the serum levels of vitamin D reduced in HT?Methods: We examined the medical records of the ‘Thyroid policlinic’ patients with or without HT. Vitamin D, thyroid autoa...

ea0026p463 | Thyroid cancer | ECE2011

Comparison of clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma

Akarsu Ersin , Metin Sevim Mehmet , Ozsan Muge , Erkilic Suna , Araz Mustafa

Papillary thyroid carcinoma (PTC) is most frequent endocrine cancer on the other hand papillary microcarcinoma can be seen increasing frequency in recent years. In this study we compare clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma retrospectively.Eighty one PTC and 38 PMC total 119 patients followed between 2005 and 2009 were enrolled study. Average follow-up time is 35 months in PTC a...

ea0026p476 | Thyroid cancer | ECE2011

Failure to supress TSH level in a thyroid cancer patient; a case report

Gedik Arzu , Yilmaz Merve , Gumus Tugba , Calan Mehmet , Soyturk Mujde , Comlekci Abdurrahman

TSH supression therapy with thyroid hormone is a mainstay of thyroid cancer treatment. Effectiveness of thyroid hormone therapy may be disrupted by nonadherence of the patient, interfering drugs, foods and intestinal disorders. We here present a case of papillary thyroid cancer with unsuccessful supression therapy.Case: A 38 year old woman, underwent total thyroidectomy for euthyroid multinodular goitre, with a pathological diagnosis of papillary thyroid...