Endocrine Abstracts

Introduction: Radioactive iodine (RAI) therapy is widely used in the treatment of hyperthyroidism especially in patients with Graves’ disease (GD), toxic multinodular goitre (TMNG), and toxic adenoma. RAI may lead to worsening of the autoimmunity with the elevation of TSH-receptor antibody (TRAB). In this study, we aimed to compare the effects of surgery or RAI treatment on TRAB.Methods: Hyperthyroid patients were divided into three groups; patients...

Objective: Serum total sialic acid(SA) concentration is assessed as an up to date risk indicator of atherosclerosis and cardiovascular diseases.Methods: It was aimed to investigate about how SA levels are effected in overt or subclinical hypothyroidism (SH) and how it’s associated with other atherosclerosis risk factors because there is no study about these topics, though SA is intensively studied in recent years.Patients: Six...

Also cytopenies can be established in the evaluation of Graves’ disease (GD), isolated thrombocytopenia is very rare. Here, we present a case of immune thrombocytopenia incidentally found in the evaluation of GD. A 48-year-old female was admitted to our hospital with palpitation and anxiousness. The thyroid function tests were concordant with thyrotoxicosis. She had two subcentimetre nodules in the right thyroid lobe. Thyroid gland had increased iodine uptake. And thyroid...

Lesions causing primary hyperparathyroidism (PHP) can be summarised as solitary adenoma (80–85%), multiglandular hyperplasia (15%), parathyroid carcinoma (1%). While double adenomas are identified in 2–15% of the patients which are operated for PHP, triple adenomas are very rare. The case is presented because in the recent years patients who are admitted to the hospital with intense bone complaints are very unusual and multiple adenomas are also seldom. 22 years old ...

Introduction: The criteria defining the threshold size of adrenal incidentaloma (AI) are >1 cm diameter. However, data about AI ≤1 cm diameter is scant. The aim of this study is to evaluate function of adrenal masses ≤1 cm and to compare them with adrenal masses >1 cm as well as to understand the possible utility of determining salivary cortisol in diagnosis of SCS in patients with AI.Method: The study included 137 consecutive patient...

Introduction: Patients with parathyroid carcinoma (PCA) and synchronous disease in other parathyroid glands have been reported in the literature. Here, we report a patient who had persistant hypercalcemia after operated from parathyroid carcinoma and improvement of hypercalcemia after the subsequent operation from atypically localised parathyroid adenoma.Case report: A 62-year-old man presented with a history of headache, fatigue, and nervousness. Labora...

Background: Adrenocortical carcinoma (ACC) is a very rare but typically aggressive malignancy. About one to three quarters of ACC is functioning with excess hormonal production.Case: A 44-year-old female patient was admitted to out-patient clinic with obesity, oligomenorrhea and abdominal pain. She had central obesity, buffalo hump, and palpable flank mass. Hypertension, transient ischemic attack, and epilepsy history was present.S...

Introduction: Anaplastic thyroid carcinomas (ATCs) are sometimes accompanied by well-differentiated carcinomas (WDCs), and ATCs have been speculated to be dedifferentiated from the preexisting or coexisting WDCs. We will present two cases determined with both ATC and papillary thyroid carcinoma (PTC.)Case 1: A 82-year-old woman was investigated due to a painful neck mass. Thyroid function tests were normal. Thyroid ultrasonography revealed isohypoechoic ...

A 67–year-old female patient was transferred to our hospital from a nursing home for high capillary glucose levels and foot ulcer considered as diabetic foot infection. Her past medical history could not be obtained because of mental retardation with unknown etiology and absence of relatives.A purulent foot ulcer sized 4×3 cm was found in right heel. She also had deformities in her hands, feet, and her nose. Peripheral neuropathy was also detec...

Introduction: Polycycstic ovary syndrome (PCOS) is an important disorder in women of reproductive age which is characterised with menstrual dysfunction, anovulation and hyperandrogenism. 5–10% of the female population affected by this syndrome. Nesfatin-1 is a new anorexigenic hormone which is expressed from several regions of hypothalamus and peripheral tissues. Nesfatin-1 is related with obesity, insulin resistance and appetite. We aimed to evaluated the nesfatin-1 leve...