Endocrine Abstracts

Thrombocytopenia can be seen rarely in Graves disease (GD). In this report we present a case of pseudothrombocytopenia in a 21-year-old woman who had hyperthyroidism due to GD. A 21-year-old female admitted to our clinic with symptoms such as hair loss, anxiety, nervousness and tremor in hands. Considering her symptoms, thyroid function tests were evaluated to screen for presence of hyperthyoidism. Her TSH level was low while free T3 and free T4 levels we...

Introduction: Ectopic ACTH secretion by pheochromocytoma causing Cushing’s syndrome has been reported rarely. Here, we present a patient with ectopic ACTH-dependent Cushing’s syndrome, caused by a pheochromocytoma with normal fractionated 24 h urinary catecholamines and metanephrines.Case report: A 48-year old female patient admitted to our clinics with the complaints of severe hypertension despite receiving anti hypertensive therapy. Severe he...

Brown tumor is a non-neoplastic lesion which resulting from abnormal bone metabolism caused by hyperparathyroidism. We report a rare case of peripheral brown tumor related with primary hyperparathyroidism which simulating a peripheral giant cell granuloma of the jaws.Introduction: PHPT occurs in a setting of excessive parathyroid hormone (PTH) secretion which resulting in hypercalcemia.Case report: A 50-year-old man was admitted to...

Introduction: Oncogenic osteomalasia is a rare paraneoplastic syndrome in which a tumor produces fibroblast growth factor 23 which leads to increased urinary phosphate excretion resulting in hypophosphatemia. It is frequently associated with mesenchymal tumors of bone and soft tissues. We report a case of oncogenic osteomalasia due to lipoma.Case report: A 38-year-old female patient with a 6-year history of left hip pain which progressively worsened over...

Introduction: Two tumors originating from different cells in the thyroid to metastasis same lymph nodes is very rare. We aimed to present that the same lymph node metastasis of medullary and papillary thyroid in a case.Case: A 4-year-old male presented with backache without a formerly known disease, has no other property in the patient’s history. Vertebra BT was taken and T2, T4, T6 vertebral metastasis have been det...

Background and aims: Fetal, maternal and perinatal complications are increased in pregnant women with type 1 diabetes mellitus (T1DM). In this study, we aimed to evaluate the effects of CSII on pregnancy outcomes, glycemic control and acute complications in pregnant women with T1DM.Materials and methods: We retrospectively analyzed the data of women with T1DM, who were on CSII therapy during their pregnancy, followed at our clinic between 2008 and 2012. ...

Objective: Thyroid diseases are among the most common endocrine disease and with a prevalence of 1.2%. Thyroid hormones have several effects on cardiovascular system. Many studies showed the association between hyperthyroidism and acute ischemic heart disease with conflicting results. Epicardial adipose tissue (EAT) thickness is a marker of atherosclerosis and independent predictor of coronary artery disease. In this study, we aimed to evaluate the EAT thickness in patients wi...

Introduction: Neuroendocrine tumors (NETs) are rare tumors harboring overexpression of somatostatin receptors (SSTRs) on their cell membrane. Gallium 68-tetraazacyclododecane tetraacetic acid-octreotate (68Ga-DOTATATE) positron emission tomography/computed tomography (PET/CT) is an important imaging modality in diagnosis and staging of NETs. Because some organs such as spleen, adrenal glands and liver physiologically express SSTR, it might be challenging to distinguish some pa...

Introduction: In pregnancy, the incidence of Primary Hyperparathyroidism is 1%; and there are 80% adenoma, 15% parathyroid hyperplasia, 3% multiple adenoma, and 1% parathyroid carcinoma in its etiology. In pregnancy, serum calcium (Ca) levels may not rise as much as expected. This is associated with hypoalbuminemia, GFR increase, placental Ca transfer, and inhibition of PTH–related bone resorption by estrogen. In pregnancy, hyperparathyroidism is asymptomatic at a rate o...

Introduction: Studies investigating the association between serum IGF-1, and thyroid nodule, ovarian or thyroid volume in polycystic ovarian syndrome (PCOS) are limited. We aimed to analyze the association between serum IGF-1 level, and ovarian or thyroid volume, or thyroid nodule in PCOS.Materials and methods: The study was performed between June 2017 and August 2019 as prospective design. The patients referred to our medical faculty were included. Adul...