Endocrine Abstracts

Aim: Bisphenol A (BPA) is the most common endocrine disruptor among environmental estrogens. BPA is an ingredient that is commonly used in polycarbonate plastics. In this study, our main concern is to measure the levels of BPA in premenopausal obese women and to examine the relationship of BPA with adiponectin and leptin.Materials and methods: 47 obese women and 39 non-obese healthy women were enrolled in this study. All participants were premenopausal. ...

Introduction: Several studies have shown that prediabetic patients had increased concentrations of inflammatory markers and this association is independent of underlying obesity. Netrophil to lymphocyte ratio (NLR) is considered as a new inflammatory marker and has been studied extensively in a variety of clinical conditions especially in solid tumours and cardiovascular diseases. Studies evaluating the subclinical inflammation in prediabetes revealed positive association of s...

Aim: Disabilities of the arm, shoulder, and hand (DASH) questionnaire is a self-administered region-specific outcome instrument developed as a measure of self-rated upper-extremity disability and symptoms. The DASH consists mainly of a 30-item disability/symptom scale. In this study, we aimed to evaluate DASH questionnaire in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and 10...

Aim: In this study, we aimed to assess psychiatric symptoms in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and 107 men) who had T2DM were included as a preliminary in this study. The presence of cheiroarthropathy, Dupuytren’s contracture, tinnel sign, and tendinitis was assessed. Diabetic retinopathy was assessed by direct ophthalmoscopy. Urinary albumin excretion was de...

Aim: Diabetes mellitus is a chronic metabolic condition characterised by persistent hyperglycaemia with resultant morbidity and mortality related primarily to its associated microvascular and macrovascular complications In this study our aim was to investigate the prevalence of the most frequently occurring hand complications in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and...

Aim: The intima–media thickness (IMT) measurement of the common carotid artery is recognised as an important marker of systemic atherosclerosis. It may be useful in predicting the cardiovascular events, since it is related to the severity of coronary artery disease. The aims of this study were to analyse whether correlations exist between the IMT of the common carotid artery and the main clinical and biochemical parameters in patients with primary hyperparathyroidism (PHP...

Aim: To evaluate serum and intranodular vascular endothelial growth factor (VEGF) and vascular endothelial growth factor receptor-1 (VEGFR-1) level thyroid nodules and explore its relevance to ultrasound feature/pathological results.Methods: A total of 80 patients (62 women and 18 men) with thyroid nodules were included in this prospective study. Thyroid function tests, fine needle aspiration biopsies, ultrasonographic and scintigraphic evaluation were r...

Introduction: Multiple endocrine neoplasia type 2A (MEN2A) is a complex autosomal dominant inherited syndrome characterized by medullary thyroid carcinoma (MTC), phaeochromocytoma, and primary parathyroid hyperplasia (PPH). In patients with only one or two clinical features, identification of a germline rearranged in transfection (RET) mutation or the identification of the clinical features of MEN2A in other first degree relatives is required to make the diagnosis. We present ...

Introduction: Gestational diabetes mellitus (GDM) is a sort of temporary carbonhydrate intolerance in pregnancy. GDM leads to a variety of risks for the fetus and the mother during pregnancy. Mothers who had GDM during their pregnancy have high risk of caesarean section and pre-eclampsia. Also there are risks of macrosomia, neonatal hypoglycemia and hyperbilirubinemia for the fetuses of these mothers. Cardiovascular disorders, hypertension, dyslipidemia and metabolic syndrome ...

Introduction: Isotretinoin (Iso) treatment in acne disease may cause dyslipidemia and increased liver enzymes. Its effects on lipid and glucose metabolism may cause atherogenic complications. The aim of this study was to evaluate carotis intima–media thickness (CIMT), HOMA-IR, and osteopontin (OPN) levels in acne patients on Iso treatment.Methods: Iso treatment given 21 patients are included in this study. They followed for 4 months. 21 patients wit...