Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep169 | Endocrine tumours and neoplasia | ECE2017

Respiratory symtoms lead to a diagnosis of pheochromocytoma: An unusual presentation

Teles Luis , Neves Joao Sergio , Souteiro Pedro , Oliveira Sofia Castro , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Pheochromocytoma is one of the major secondary causes of hypertension. The classic triad of pheochromocytoma symptoms of headache, sweating and tachycardia is not present in a high percentage of patients and is sometimes diagnosed as incidentaloma or atypical presentations.Case report: The authors present a 56-year-old man, with no known diseases, referred to Endocrinology evaluation by incidentaloma of the right adrenal gland, from the Pne...

ea0049ep493 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Bronze diabetes – a rare secondary cause of diabetes

Souteiro Pedro , Neves Joao Sergio , Oliveira Sofia Castro , Belo Sandra , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Secondary causes of diabetes refer to a category in which diabetes is associated with other diseases. They are thought to constitute less than 2% of the total cases of diabetes.Case report: A 56 year-old caucasian man, with no relevant medical history, presented to the Emergency Department with fatigue, polyuria, polydipsia, polyphagia and involuntary weight loss (6 kg in two weeks). He was hemodynamically stable and exhibited a glycaemia o...

ea0049ep613 | Diabetes therapy | ECE2017

The insulin delivery system and its impact on quality of life and on psychopathological symptomatology

Pereira Miguel , Neves Celestino , Esteves Cesar , Oliveira Sofia , Arteiro Cristina , Coelho Rui , Carvalho Davide

Introduction: In chronic diseases a good psychological and behavioral adaptation is essential. Concerning diabetes the Insulin Delivery System (IDS) adopted tend to be an important factor of adaptation, global satisfaction and, above all, quality of life (QoL).Objectives: To analyze the QoL and IDS satisfaction and its relationship with psychopathological symptomatology in patients on continuous subcutaneous insulin infusion (CSII) therapy.<p class="...

ea0049ep1081 | Pituitary - Clinical | ECE2017

Hypopituitarism and central diabetes insipidus in an HIV patient – a late complication of cerebral toxoplasmosis and/or antiretrovirals?

Oliveira Sofia Castro , Souteiro Pedro , Neves Joao Sergio , Nogueira Claudia , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: The endocrine system is often affected in the course of HIV infection. However, hypopituitarism and diabetes insipidus are uncommon disorders in these patients and have been related to drugs, infections of the central nervous system and neoplastic infiltration, in extremely rare cases.Case report: We present a case of a 42-year-old man with HIV infection known since 2005, but undergoing antiretroviral therapy only since 2010 (emtricitabine/...

ea0041ep548 | Diabetes therapy | ECE2016

Intensive therapy with insulin pump in type 1 diabetes mellitus

Gouveia Ines , Neves Celestino , Oliveira Sofia , Neves Joao Sergio , Dias Claudia , Carvalho Davide

Background: Continuous subcutaneous insulin infusion (CSII), alongside multiple daily injections (MDI) are the most frequent therapeutic of type 1 Diabetes Mellitus (DM). We aimed to evaluate the effects of the transition from MDI to CSII in the treatment of type 1 DM.Patients and methods: This retrospective longitudinal study analysed patients that received treatment with CSII from 2006 to 2014. Our sample had 85 patients, 35 male (41.2%) and 50 female ...

ea0035p1017 | Thyroid (non-cancer) | ECE2014

Adipokines and cardiovascular risk factors in patients with autoimmune thyroiditis and subclinical hypothyroidism

Neves Celestino , Esteves Cesar , Sokhatska Oksana , Palmares Carmo , Carvalho Davide , Delgado Luis , Medina Jose Luis

Aim: To evaluate the serum levels of resistin and adiponectin, and the potential relationship between these adipokines, thyroid function, lipid profile, C-reactive protein (CRP) and homocysteine levels in patients with autoimmune thyroiditis (AIT) and subclinical hypothyroidism (SCH).Methods: patients with AIT (58 females; 47.7±16.7 years) were studied; 33 of them had also SCH. These patients were diagnosed by a positive result in an anti-peroxidase...

ea0020p413 | Diabetes and Cardiovascular | ECE2009

Quality of life in diabetes mellitus: conditional issues of treatment and coping strategies

Pereira Miguel , Neves Celestino , Pereira Joao , Carqueja Eduardo , Alves Marta , Carvalho Davide , Coelho Rui , Medina Jose

Introduction: Quality of life (QoL) is a subject of increasing interest in the health context. Applied to a chronic condition like diabetes, this issue could give an overall perspective of the health outcome.Objective: To evaluate the coping mechanisms, the treatment issues and its contribution to QoL of diabetes patients.Patients and methods: We gathered a sample of 94 diabetic subjects, 50% males, 55.3% type 1, with a mean age of...

ea0056p402 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Major adverse cardiovascular events and in-hospital outcomes in patients with diabetes

Neves Celestino , Sergio Neves Joao , Oliveira Sofia Castro , Pereira Miguel , Oliveira Ana , Carvalho Davide

Background: Diabetes is an important risk factor for major adverse cardiovascular events (MACE). Although the increased risk for MACE is well known, the impact on the in-hospital outcomes remains incompletely understood. Our aim was to evaluate the interrelation between diabetes and MACE in a central hospital in the North of Portugal between 2009 and 2015.Methods: We evaluated retrospectively the hospitalizations due to MACE including stroke or transient...

ea0084ps2-07-60 | Graves’ Disease 1 | ETA2022

Polymorphisms in proinflammatory cytokines’ genes and lipid profile in patients with graves’ disease

Neves Celestino , Sergio Neves Joao , Goncalves Juliana , Soares Paula , Delgado Luis , Carvalho Davide

Objective: Graves’ Disease (GD) is one of the most common autoimmune disorders. Some SNP in pro-inflammatory cytokines have already been linked to an increased susceptibility of developing GD. Thyroid hormones are crucial modulators of lipid metabolism. A pro-inflammatory state, may contribute several metabolic changes, including disturbances in lipid metabolism. Our aim was to evaluate if SNP in pro-inflammatory cytokines also contribute to disturbances of lipid profile ...

ea0049ep194 | Endocrine tumours and neoplasia | ECE2017

Acinic cell adenocarcinoma of the parotid gland associated with paraneoplastic Cushing’s syndrome – a rare clinical case

Castro Oliveira Sofia , Sergio Neves Joao , Souteiro Pedro , Belo Sandra , Isabel Oliveira Ana , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Primary acinic cell carcinoma (ACC) is an uncommon salivary gland (SG) tumor, making up 1–3% of all SG neoplasms, more frequent in women, at 40–60 year old. The cause is still unknown and the only well-established risk factor is ionizing radiation. ACC metastasize in 10–15% of the cases, 35% tends to recur and the rate of disease-associated death is about 16%. Surgical resection is the mainstay treatment, but radiation therapy may be used in some c...