Endocrine Abstracts

Members of a hospital staff (n=332) were invited to complete a survey outlining dietary and lifestyle behaviour, and indicate if they were interested in a weight management programme. Height and weight were measured and body mass index (BMI) was calculated, in all respondents.Two hundred and sixty (78%) staff members responded, 60 males (23.1%) and 200 females (76.9%). The mean age of respondents was 36.5 yrs (35.8yrs males, 36.7yrs female). The mean bo...

Background: Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive inherited disorder resulting in the inability to breakdown medium-chain fatty acids to provide energy during periods of low-calorie intake and hypoglycaemia (infections, fasting, vomiting). Without urgent treatment, the accumulation of toxic fatty acids leads to encephalopathy and sudden death.Pregnant females with Type 1 diabetes requ...

Background: Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive inherited disorder resulting in the inability to breakdown medium-chain fatty acids to provide energy during periods of low-calorie intake and hypoglycaemia (infections, fasting, vomiting). Without urgent treatment, the accumulation of toxic fatty acids leads to encephalopathy and sudden death.Pregnant females with Type 1 diabetes requ...

Introduction: Mild hypercalcaemia can occur in patients with Graves’ disease. Postulated mechanisms include increased bone resorption and mobilisation of calcium from the bones in response to increased interleukin-6 and catecholamine levels. The coexistence of primary hyperparathyroidism and Graves’ disease is rare. Hypercalcaemia with suppressed or unsuppressed parathyroid hormone levels should prompt a search for non-parathyroid or parathyroid causes, respectively....

Aim: To evaluate the feasibility of non-face to face (NFTF) contact in the follow-up for patients with thyrotoxicosis on carbimazole therapy.Background: While on carbimazole, achievement of a euthyroid state may involve multiple clinic appointments. We hypothesize by conducting these appointments in a NFTF setting, i.e. telephone consultation with trained nurse practitioner supported by an Endocrine consultant; a higher volume of consultations can occur ...

Introduction: Limbic encephalitis is characterised by seizures, changes in personality and memory impairment. Syndrome of inappropriate antidiuretic hormone secretion (SIADH) associated with autoimmune limbic encephalitis is rare. We present an interesting case.Case: A 57-year-old gentleman presented with seizures and a cardiac arrest. He had a past history of excess alcohol intake and had been taking excess alcohol prior to this event. Physical examinat...

Introduction: Klinefelter’s syndrome (KFS) is associated with an increased risk of certain malignancies; including leukemia, breast cancer and mediastinal germ cell tumours. Testicular tumours are uncommon. Epidermoid cysts are benign tumours of hair-growing areas. Testicular epidermoid cysts are very rare and account for 1–2% of all testicular tumours. We report a rare case of bilateral epidermoid cysts in a patient with Klinefelter’s syndrome.<p class="abs...

Introduction: Patients with hypothyroidism are routinely advised to take levothyroxine without food or beverages but the pharmacokinetic effect of many common foods are unknown. We describe a patient with an unusually high levothyroxine requirement who only achieved adequate replacement by taking grapes along with levothyroxine. Through a cycle of challenge, withdrawal, and-re-challenge, we were able to demonstrate that levothyroxine availability was enhanced by grapes in this...

Introduction: Anti-phospholipid syndrome is characterised by the presence of arterial or venous thrombosis, it is autoimmune in nature and manifests as a systemic disease. Adrenal vein haemorrhagic infarction which is a sequel of adrenal vein thrombosis ultimately leads to loss of adrenal function, it is one of the presentations of anti-phospholipid syndrome especially with catastrophic type. In one analysis adrenal involvement was reported in only 13% of the reported cases of...

A 30-year-old male was admitted to the neurotraumatology ward after head trauma with cerebral concussion, subdural & subarachnoidal haemorrhage. The Endocrinologist was called to evaluate high urinary debits. The patient was healthy until 4 years before admission. He enrolled on variate patterns of alimentary restriction that resulted in the loss of 28 kg. Since then he had visited multiple doctors (Cardiology, Haemathology, Psychiatry, Gastroenterology, Urology, Endocrino...