Endocrine Abstracts

Introduction: Single-electrolyte derangement is a common biochemical finding. Multiple-electrolytes derangement is less common and require multiple and simultaneous corrective therapies. We present a patient who had multiple admissions with multiple-electrolytes derangement, which after further evaluation required a single therapeutic intervention.Case: A 26-year-old lady had eight admissions over three years with abdominal pain and vomiting. During each...

Introduction: Hyponatraemia is the commonest electrolyte disturbance affecting patients in and out of hospital. Streamlining and improving the investigation of hyponatraemia will quicken diagnosis, improve patient outcomes and prevent deterioration and unnecessary stay in hospital. We aimed to audit the assessment of patients with hyponatraemia against our existing guidelines (Hyponatraemia – An Investigator’s Checklist).<p class="abst...

Introduction: Radioiodine is used for the treatment of Thyrotoxicosis when medical treatment (anti-thyroid drugs) has failed or cannot be tolerated and surgical treatment is not an option. Our previous audit in 2011 demonstrated substantial adherence to the Royal College of Physicians (RCP) guidelines for Radioiodine treatment, but one patient was lost to follow-up. It was recommended that we improve our re-call system. We aimed to re-audit our service.<p ...

Introduction: Single-electrolyte derangement is a common biochemical finding. Multiple-electrolytes derangement is less common and require multiple and simultaneous corrective therapies. We present a patient who had multiple admissions with multiple-electrolytes derangement, which after further evaluation required a single therapeutic intervention.Case: A 26-year-old lady had eight admissions over three years with abdominal pain and vomiting. During each...

Background: The mortality from COVID-19 is higher in DM patients compared to the general population. Hence, it is highly desirable that diabetic patients are vaccinated against COVID-19 infection in order to reduce their risk of contracting the disease and having devasting consequences from the infection.Aim: The aim of this study is to determine the willingness of type 2 DM patients to accept COVID-19 vaccine and the factors that influence their decisio...

Introduction: Acromegaly is a rare metabolic condition in adults caused by over secretion of growth hormone from the pituitary gland. The characteristic skeletal and organ overgrowth and dental mal-occlusion issues are so insidious that they go unnoticed by the patient and family. The dentist may be the first healthcare provider to see these patients, thereby proving instrumental in early diagnosis. We report two cases of acromegaly: one case identified by a dentist and anothe...

Introduction: Persistent symptoms of hypothyroidism or raised levels of thyroid stimulating hormone (TSH) despite adequate levothyroxine replacement (>1.6 µg/kg body weight) suggest treatment-refractory hypothyroidism. Adherence to treatment and conditions that might impair absorption or increase demand for levothyroxine should be explored.Case: A 51-year-old man presented with raised TSH levels despite being on 425 mg daily of levothyroxine. He...

Background: The prevalence of iodine-based contrast media-induced (ICM-induced) thyroid dysfunction varies (1-15%). Contrast-induced hyperthyroidism is predominantly found in iodine-deficient regions and in patients with underlying nodular goitre or latent Graves’ disease. Beta-blockers are first-line therapy, but anti-thyroid medication are used for severe symptomatic cases.Case Report: A 79-year-old man presented with a 4-day history of bilious vo...

Endocrine-Related Cancer, 2018, 25(2): 131–144 (DOI: https://doi.org/10.1530/ERC-17-0415)...

Introduction: Gastric bypass surgery is performed for intractable severe reflux oesophagitis not amenable to vagotomy and pyloroplasty. Long-term complications include dumping syndrome, nutritional deficiencies, incisional hernia and weight loss. We report a case of unexplained adrenal insufficiency in a patient who had gastric bypass surgery.Case: A 77-year-old gentleman presented with a history of recurrent hypoglycaemic episodes. Hypoglycaemic symptom...