Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep573 | Thyroid | ECE2024

Asymptomatic subacute thyroiditis presenting as bilateral thyroid nodules and pyrexia of unknown origin

Kaliakatsou Eirini , Fountas Athanasios , Papanastasiou Labrini , Pikou Vasiliki , Koutete Dimitra , Mpaltas Christos , Markou Athina

Introduction: Subacute thyroiditis (SAT) is an acute inflammatory disorder which can rarely present as pyrexia of unknown origin without other symptoms. Diffuse thyroid heterogeneity, focal hypoechoic areas and decreased/normal gland vascularity are the most common ultrasound findings of SAT. We report a case of asymptomatic SAT presenting as bilateral thyroid nodules and pyrexia of unknown origin.Case Presentation: A 72-year-old male with a history of t...

ea0081p522 | Adrenal and Cardiovascular Endocrinology | ECE2022

Gastric monomorphic epitheliotropic intestinal T-cell lymphoma with bilateral adrenal metastases

Kaliakatsou Eirini , Markou Athina , Papanastasiou Labrini , Giagourta Irini , Kalantzi Athanasia , Dimitriadi Anastasia , Lenos Michael , Kounadi Theodora , Fountas Athanasios

Introduction: Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL), formerly known as type II enteropathy-associated T-cell lymphoma, is a rare and aggressive subtype of lymphoma of the gastrointestinal track typically noted in Asian or Hispanic populations. Adrenal involvement as part of MEITL is extremely rare. Herein we present a patient of Greek origin with MEITL and bilateral adrenal metastases.Case Presentation: A 74-year-old man presente...

ea0063p91 | Calcium and Bone 1 | ECE2019

Effectiveness of intramuscular Ergocalciferol treatment in a patient with o steomalaciadueto severe vitamin D deficiencyafterbariatric surgery

Papanastasiou Labrini , Gravvanis Christos , Tournis Symeon , Markou Athina , Kalantzi Athanasia , Zoulias Manolis , Georgakopoulou Georgia , Pagoni Stamatina , Kounadi Theodora

Bariatric surgery is a common treatment for morbidly obese patients requiring weight loss and/or metabolic control. Vitamin D (VitD) deficiency and bone loss may occur post-operatively and supplementation with high oral doses of Vitamin D is required. Alternatively, intramuscular depot ergocalciferol (vitamin D2) which slowly releases VitD and overcomes the gastrointestinal tract, could be administrated in such patients.Aim: To present a case of severe V...

ea0041gp23 | Adrenal (2) | ECE2016

Deterioration of indices of insulin resistance in patients with non-functioning and cortisol secreting adrenal incidentalomas during a long term follow-up

Papanastasiou Labrini , Alexandraki Krystallenia , Fountoulakis Stelios , Kounadi Theodora , Markou Athina , Tsiavos Vaios , Androulakis Ioannis , Samara Christianna , Piaditis George , Kaltsas Gregory

Introduction: Adrenal incidentalomas (AI) with or without concomitant autonomous cortisol secretion can be associated with several metabolic alterations that may lead to increased cardiovascular risk. However, data regarding insulin resistance (IR) during long term follow-up of AI are scarce. The aim was to prospectively investigate the presence and evolution of IR in patients with AI between 2003 and 2014.Methods: Seventy three patients with AI for at l...

ea0035p979 | Thyroid (non-cancer) | ECE2014

Ultrasound-guided thyroid fine needle aspiration with rapid on-site evaluation of adequacy: data from the clinic of endocrinology of a Greek tertiary general hospital in 2013

Fountoulakis Stelios , Papanastasiou Labrini , Koutmos Spiros , Charalambous Pinelopi , Stratigaki Aimilia , Panagouli Pelagia , Lazari Paraskevi , Asimis Eleptherios , Vlahou Melpomeni , Piaditis George

Introduction: Ultrasound-guided fine needle aspiration biopsy (US-FNAB) enables selective sampling of thyroid follicular cells while minimizing potential complications. Inadequate specimen sampling can lead to FNAB repeat. Our aim was to evaluate the morphological and cytological characteristics of thyroid nodules with US and rapid on-site evaluation of adequacy (ROSE).Methods: Two independent endocrinologists evaluated nodule characteristics of 171 US-F...

ea0070aep63 | Adrenal and Cardiovascular Endocrinology | ECE2020

Surgical outcomes of adrenalectomy for primary hyperaldosteronism after using novel diagnostic tests

Alexandraki Krystallenia , Markou Athina , Papanastasiou Labrini , Tyfoxylou Ernestini , Kapsali Chara , Gravvanis Christos , Kaltsas Gregory , Zografos Giorgos , Piaditis George

Background: Primary hyperaldosteronism (PHA) is the most frequent type of endocrine hypertension with a prevalence that is continuously rising. Following the introduction of diagnostic tests that consider both the adrenocorticotropic hormone effect andrenin–angiotensin–aldosterone system (RAAS), the post-dexamethasone saline infusion test (D-SIT) and the overnight dexamethasone, captopril, valsartan test (DCVT) using pharmaceutical RAAS blockade, a higher prevalenc...

ea0022p378 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Identification of a novel mutation of MEN1 gene in a patient with persisting primary hyperparathyroidism

Papanastasiou Labrini , Prevoli Anastasia , Pappa Theodora , Kamakari Smaragda , Kafritsa Paraskevi , Metaxa-Mariatou Vassiliki , Markou Athina , Piaditis George

Background: Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant disorder characterized by the presence of endocrine and nonendocrine tumors. Until recently, more than 450 different germline mutations have been reported in MEN1 patients involving frameshift deletions, insertions, as well as nonsense mutations.Aim: To report a novel mutation in MEN1 gene in a young female with persisting primary hyperparathyroidism.<p class="ab...

ea0022p548 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Evaluation of adrenal morphological and functional alterations in acromegalic patients

Pappa Theodora , Papanastasiou Labrini , Tsiavos Vaios , Tseniklidi Ermioni , Androulakis Ioannis , Tsounas Panagiotis , Roussaki Peggy , Kaltsas Gregory , Piaditis George

Introduction: Acromegaly is well known to induce hypertrophy and hyperplasia in many organs, i.e. thyroid gland, colon, prostate. This action is presumably exerted by the elevated GH and IGF1 levels. In our study, we investigated the alterations of the adrenal glands seen in acromegaly.Aim: To assess the changes in adrenal morphology and functional status in a series of patients with acromegaly.Subjects and methods: Fifty-four acro...

ea0056p92 | Clinical case reports - Pituitary/Adrenal | ECE2018

Severe pheochromocytoma crisis, Type B, resulting in Takotsubo-like cardiomyopathy and fulminant refractory cardiogenic shock, successfully treated with extracorporeal membrane oxygenation (ECMO) but with fatal neurological sequelae for the patient.

Tyfoxylou Ernestini , Kounadi Theodora , Markou Athina , Papanastasiou Labrini , Charalampidou Liana , Kyriazi Evangelia , Voulgaris Nikolaos , Neoklis Skampas , Pyrgakis Vlassios , Piaditis George

Introduction: Catecholamine excess causes profound vasoconstriction, resulting in reduced intravascular volume. Pheochromocytoma crisis can be further complicated with acute stress (Takotsubo-like) cardiomyopathy, attributed to the toxic catecholamine effect on the myocardium, and cardiogenic shock leading to tissue ischemia.Aim: To present a rare case of pheochromocytoma crisis, complicated with fulminant cardiogenic shock, which led to life-threatening...

ea0073oc1.4 | Oral Communications 1: Adrenal and Cardiovascular Endocrinology | ECE2021

The impact of targeted treatment on echocardiographic indices in patients with overt and mild primary aldosteronism, compared to patients with essential hypertension.

Gravvanis Christos , Papanastasiou Labrini , Kaoukis Andreas , Glikofridi Spyridoula , Monastirioti Nicoleta , Voulgaris Nikolaos , Ernestini Tyfoxylou , Markou Athina , GeorgePiaditis

IntroductionPrimary aldosteronism (PA) is associated with cardiovascular events and target organ damage, such as left ventricular (LV) hypertrophy and cardiac dysfunction. However the impact of subtle aldosterone secretion on cardiac function has not yet been evaluated.AimTo prospectively evaluate the cardiac function using echocardiographic indices in patients with biochemical overt, mild PA and essential hy...