Searchable abstracts of presentations at key conferences in endocrinology

ea0011p285 | Diabetes, metabolism and cardiovascular | ECE2006

Associations between bmi and smoking with reference to other life style factors, the 4th and the 5th Tromsø studies

Sneve M , Jorde R

Objective: To explore the relationship between body mass index (BMI) and smoking in a cross-sectional and longitudinal study.Methods: In the 4th and 5th Tromsø studies in 1994 and 2001, 27158 and 8130 subjects participated. Height and weight were measured and a questionnaire on life style factors filled in.Results: Complete datasets were available for 10920 men and 12092 women in the 4th Tromsø study. Among these subjects...

ea0011p618 | Neuroendocrinology and behaviour | ECE2006

Night sleep affected by salt

Samadie R , Heydarpour F

Introduction: Salt in the principal supply of sodium. In normal conditions the average daily salt intake of Iranian adults is 5–15 gr. 4–6 spoonfuls of salt in a day can be lethal, but for soldiers in equatorial regions 50 grams of salt in a day may be needed. In this study the effects of salt on night sleep was addressed.Method: 20 volunteer students were chosen for the study. They had no problem sleeping before the study. They recorded the ti...

ea0011p619 | Neuroendocrinology and behaviour | ECE2006

ADH and Thirst Function in Defence with Hypernatremia Formation

Samadie R , Heydarpour F

Introduction: Thirst and ADH secretion are two principle mechanisms for controlling body fluid osmolarity. Even an excessive load of salt can effectively be handled by these systems. We studied the effect of salt solution consumption on serum sodium level and osmolarity and the action of these two systems.Method: Seven groups each consisting of 6 male rats weighing 200±20 gr. were chosen. Salt solutions (1,3,5, 7 and 9%) were also provided. The rats...

ea0009p198 | Clinical | BES2005

Bromocriptine-sensitive acidophil-stem-cell adenoma co-secreting growth hormone and prolactin - A case report

D'Costa R , Kalk W

Case HistoryWe report a 28-year-old man who presented initially to our ENT department with 3-year history of intermittent epistaxis subsequently found to have an extensive acidophil-stem-cell adenoma, rare pituitary tumours usually unresponsive to dopamine agonists requiring radiotherapy and somatostatin analogues in resistant cases.He was clinically acromegalic, demonstrating an elevated Growth Hormone (GH) 17.9 milliunits per lit...

ea0007p131 | Growth and development | BES2004

Do prolonged courses of testosterone affect final height in extreme maturational delay?

Lee R , Butler G

Aim: Differentiating idiopathic hypogonadotrophic hypogonadism from extreme maturational delay can be difficult, so most boys receive testosterone (T) replacement until the diagnosis becomes clear. Standard 3 month T therapy for maturational delay does not diminish adult stature, so we set out to determine whether T treatment of greater than 6 months duration would have an adverse effect on final height (FH) in boys with the eventual diagnosis of extreme maturational delay.</p...

ea0007p252 | Clinical case reports | BES2004

Paradoxical urine and plasma cortisol response to dexamethasone: probable Carney Complex with micronodular adrenal hyperplasia

Raskauskiene D , Clayton R

Dexamethasone is frequently used in diagnostic work-up of patients suspected of having Cushing's syndrome. We report the case of a young woman whose cortisol production paradoxically increased following dexamethasone administration. A 27 years old woman presented with intermittent facial rounding (see photos), weight gain (6 kg), hirsuitism, spontaneous bruising, menstrual irregularity. On examination the only feature to suggest Cushing's syndrome was very thin skin on the bac...

ea0006p36 | Endocrine tumours and neoplasia | SFE2003

Macroprolactinomas in men: long-term efficacy of bromocriptine treatment

Chattopadhyay A , Bhansali A , Dash R

Gender-specific differences in tumor size at clinical presentation and possible differences in tumor biology make it important to determine treatment outcomes of male patients with bromocriptine [BRC]. We retrospectively analysed treatment response to bromocriptine in 29 male patients with macroprolactinoma (15) and giant macroprolactinoma (14). The duration of treatment was 6-96 months (mean 22.7). Clinical features at presentation included headache (21, 72.4%), visual field ...

ea0005p32 | Clinical Case Reports | BES2003

Infantile methylmalonic aciduria caused by maternal pernicious anaemia

Wills C , Page R

A 5-month-old child presented with progressive lethargy and loss of motor skills. His mother had pre-existing type 1 diabetes with good glycaemic control throughout gestation (HBA1c 7.3% at booking, 5.5% at 20 weeks). She was euthyroid during pregnancy but had a high titre of thyroid microsomal antibodies (25600). Full blood count was normal at booking and delivery (haemoglobin 12.3 and 11.8 grams per decilitre, MCV 83 and 84 respectively). She was not vegetarian.The child...

ea0005p52 | Clinical Case Reports | BES2003

Concurrence of primary hypothyroidism, epilepsy and benign intracranial hypertension in an adult

Dashora U , Kennedy R

A 35-year-old lady presented 20 years ago with difficulty in walking. She was born in Newcastle and was brought up by her mother with no contact with father. Early childhood was further traumatised when mother moved in with a man affected from multiple sclerosis with whom she never adjusted. Consequently, she was placed with two foster parents but could not adjust there either. Two years earlier, she was admitted in hospital with drug overdose. By age 25, she had hypothyroidis...