Endocrine Abstracts

Diabetic peripheral neuropathy (DPN) is a most common complication of diabetes mellitus. Patients with DPN have chronic, painful symptoms that disrupt sleep, depressed mood and can lead to diminish quality of life. We evaluated clinical characteristics of diabetic peripheral neuropathy in past and present in KoreaWe performed the study to determine the prevalence and to understand the clinical characteristics of diabetic peripheral neuropathy in Koreans ...

Introduction: The inability to achieve and maintain an erection sufficient for satisfactory sexual intercourse is a distressing and common symptom in Bangladeshi Diabetic subjects.Aims and Objectives: The purpose of this study is to present a framework for cost effective evaluation & treatment. Because many of the diabetic subjects usually suffers from psychological stress since he is detected as diabetic and many of them believe in Myths that diabet...

Aim: The work was initiated to study depression manifestations in patients with primary hyperparathyroidism.Materials and methods: Symptoms of anxiety and depression were assessed in 67 patients with primary hyperthyroidism aged from 16 to 30 years examined by means of Spielberger–Khanin’s test and Beck’s Depression Inventory.Problem of marginal psychoneurotic disturbances in patients with various somatic pathologies...

Menopausal status is associated with weight gain, increased central fat mass, abnormal lipid metabolism, insulin resistance, and susceptibility to metabolic syndrome (MetS). Leptin is synthesized and secreted by adipocytes. Serum leptin levels are highly correlated with fat mass. We determined the association between MetS and serum leptin levels in 153 postmenopausal women. The difference in serum leptin level between MetS and non-MetS groups showed a statistical significance ...

Introduction: Cytokines have been suggested to be involved in modulating anti-tumor responses and promoting tumor growth. Some studies have indicated that cytokines could also be involved in the pathogenesis of pituitary tumors. Th17 cells, characterized by expression of several cytokines as interleukin 22 (IL 22), might have a role in tumor immune-surveillance. IL-22 is a cytokine involved in the modulation of tissue responses during inflammation and, through activation of St...

We describe the course of a now 24y/o M with congenital hypopituitarism, severe micropenis, cryptorchidism, hypoplastic testes, hypospadiasis and pulmonic stenosis. He presented with neonatal hypoglycemia. MRI showed small anterior pituitary and ectopic posterior pituitary near tuberous cinereum. Pulmonic stenosis detected after auscultation of a murmur, was mild grade on echo. Free T4 1 ng/dl (1–2.5) TSH 6.7 μU/ml (0.2–6) glucagon stimulation for GH ...

We conducted this study to determine the degree of obesity influence on the hypoglycemic response of growth hormone and cortisol after weight loss of 5%. A total of 45 non-diabetic, male subjects followed in the outpatient endocrinological department were divided into three groups comprising 15 subjects in each group, based upon body mass index (BMI) to healthy, overweight and obese group. Metformin was administered in the dose of 500 mg daily to the overweight and obese parti...

Few data on prevalence of thyroid diseases in neoplastic groups of patients has been reported. A slight increased prevalence of hypothyroidism and autoimmune thyroiditis in patients with breast cancer and cutaneous melanoma are been described.Aim: Of the study was to evaluate the prevalence of thyroid diseases in a group of non-endocrine neoplasm consecutively evaluated by the oncologist and endocrinologist in a iodine-sufficient area of north-east Italy...

Wistar rats (male) were divided into three groups – group A (GA) served as control, group B (GB) were daily administered orally chlorpyrifos at a dose of 5 mg/kg b wt. and animals in group C (GC) received daily an oral administration of chlorpyrifos at a dose of 10 mg/kg b wt. Rats were sacrificed on 1st, 2nd, 4th, 6th, and 8th week after initiation of the experiment. Changes in serum electrolytes (calcium, phosphate and magnesium) and endocrine glands (calcitonin cells a...

Background: Recent reports have mentioned rising incidence of thyroid cancer (TC) detected before and after thyroidec-tomy (Tx) for hyperthyroidism but “hyperfunctioning” TC is however a rare entity.Patients & Methods: Among a personal series of 464 patients which underwent Tx including 147 (33.6%) cases of thyroto-xicosis and 72 (13.6%) cases of TC, we founded 10 patients with hyperthyroidism and nodular or microscopic TC but only one case...