Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep915 | Pituitary - Clinical | ECE2016

Prolactin measurements improve the diagnostic accuracy of inferior petrosal sinus sampling

Uygur Meliha Melin , Yasar Mehmet , Deyneli Oguzhan , Yavuz Dilek Gogas

Introduction: Inferior petrosal sinus sampling for ACTH is the current gold standard test for the differentiation of pituitary Cushing disease from the ectopic ACTH syndrome. Early studies with İPSS reported a diagnostic sensitive and specificity approaching 100%, additional experience has shown a false negative rate of 1-10%. This has been due to either technical problem with unsuccessful petrosal sinus catheterization or anomalous venous drainage of the pituitary. The ...

ea0056p180 | Bone ' Osteoporosis | ECE2018

Evaluation of bone mineral density and vertebral fracture incidence in a group of kidney transplant recipients

Yavuz Dilek Gogas , Kahveci Arzu , Bugdayci Onur , Tuglular Serhan

Kidney transplant patients are prone to metabolic bone diseases. In this descriptive clinical study we aimed to evaluate the incidence of osteopenia osteoporosis, vertebral fractures in our group of renal transplant patients.Methods: Eighty seven patients (25 males and 62 females) aged from 20 to 67 years, who had undergone kidney transplantation 1 to 20 yrs. previously included in the study. Bone mineral densitometry was performed using dual-energy X-ra...

ea0073aep447 | General Endocrinology | ECE2021

Attitudes of physicians towards the guideline-recommended LDL target levels in diabetic dyslipidemia

Naime Afşar Satiş , Yavuz Dilek Gogas

AımThe aim of this study is to investigate the attitude of physicians, who are specialized in internal medicine, endocrinology, nurology and cardiology, on LDL target levels and antilipidemic treatments in Turkey.MethodsThis study outlines attitudes of physicians towards the guideline-recommended LDL target levels in diabetic dyslipidemia. An invitaiton to fill a questionnaire on demographic and professi...

ea0073aep471 | Pituitary and Neuroendocrinology | ECE2021

Association between fibroblast growth factor-21 and carotid intima media thickness in patients with acromegaly

Uygur Meliha Melin , Yavuz Dilek Gogas , Yazici Dilek

İntroductionThe aim of this study was to evaluate the association between fibroblast growth factor-21 (FGF-21) levels and carotid intima media thickness (CIMT) in acromegalic patients in relation to the atherosclerotic complications.Metarials and methodsThe study goroup included 70 acromegalic patients. According to the disease activity, patients cathegorized inti 2 groups: controlled and active acromega...

ea0049ep47 | Adrenal cortex (to include Cushing's) | ECE2017

Effect of adrenal mass lateralization on diagnostic tests in patients with Cushing

Tarcin Ozlem Ustay , Pehlevan Emre , Imre Eren , Uygur Melin , Deyneli Oguzhan , Yavuz Dilek Gogas

The frequency of adrenal masses is increasing in parallel with the progress of the technology. Most of these masses, which are detected by chance, are not functional, and only a part of them are exposed to an excess of hormone. The most common dysfunction in masses with hormonal activity is hypercortisolism. However, the diagnosis of Cushing’s disease is based on more than one test. In this study, we intended to compare the values of screening tests to determine whether t...

ea0049ep851 | Clinical case reports - Pituitary/Adrenal | ECE2017

Pachydermaperiostosis: a rare syndrome presented with acromegaloid changes

Uygur Meliha Melin , Arikan Izzet Hakki , Deyneli Oguzhan , Yavuz Dilek Gogas

Introduction: Pachydermoperiostosis (PDP) is a rare hereditary syndrome with familial and idiopathic forms that is characterized by subperiosteal new bone formation with pain, polyarthritis, cutis vertices grata, seborrhea, hyperhidrosis and digital clubbing. Periostosis and cutaneous thickening along with the absence of any signs of cardiovascular, pulmonary, hepatic, intestinal and mediastinal diseases causing secondary hypertrophic osteoarthropathy suggest PDP. The incidenc...

ea0041ep110 | Bone & Osteoporosis | ECE2016

Clinical characteristics of Paget disease of bone from Turkey

Yavuz Dilek Gogas , Ayturk Semra , Bayraktar Firat , Cetinkalp Sevki , PD Study Group

Prevalence of Paget’s disease (PD) of bone as well as clinical and demographical presentation may differ between the populations.Aim: In this study we evaluate clinical and demographical parameters of Paget’s disease patients followed from endocrinology clinics in Turkey.Method: An invitation was sent to all tertiary endocrinology clinics to complete a survey on demographic clinical, laboratory parameters, treatment modal...

ea0041ep144 | Calcium and Vitamin D metabolism | ECE2016

Bone mineral density is associated with hypercalciuria in primary hyperparathyroidism

Yavuz Dilek Gogas , Tekin Bahar , Buket Bayram F. , Melin Uygur M.

Aim: The most common clinical presentation of primary hyperparathyroidism (PHPT) is asymptomatıc and it is diagnosed incidentally without developing complications.In our study, we aimed to examine the characteristics of participants with primary hyperparathyroidism and the relationship between bone mineral density (BMD) and hypercalciuria.Methods: Consecutive 191 normocalciuric (24-h urinary calcium<400 mg/day) patients with PHPT (51±13 yea...

ea0041ep145 | Calcium and Vitamin D metabolism | ECE2016

Bone mineral density measurement in newly diagnosed primary hyperparathyroidism patients

Tekin Bahar , Melin Uygur M. , Buket Bayram F. , Yavuz Dilek Gogas

Aim: Clinical presentation of primary hyperparathyroidism (PHPT) differs between populations. In this study, we aimed to examine bone mineral density (BMD) and bone metabolism parameters in newly diagnosed and untreated PHPT patients in a single endocrine center in İstanbul, Turkey.Methods: Consecutive 256 PHPT patients (50.7±14 years, F/M:205/51) and 89 healthy controls (38.8±10 years, F/M:67/22) were included in the study. Serum calcium...

ea0032p848 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Advanced glycation end product associated skin autofluorescence and serum corboxymethyl lysine levels in acromegaly

Yavuz Dilek Gogas , Yalin Serap , Yazici Dilek , Yasar Mehmet , Deyneli Oguzhan

Aim: Nonenzymatic advanced glycation and oxidation end-products, advanced glycation end-products (AGEs), impart a potent impact on vessels in diabetic state and in euglycaemic conditions with increased oxidative stress.The aim of this study is to measure AGEs and its relationship with carotid intimae media thickness (CIMT) in acromegaly patients.Method: A case–control study was performed in 225 acromegalic patients (F/M: 116/1...