Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep547 | Diabetes therapy | ECE2016

The effects of vitamin D on advanced glycation end-products in prediabetic and type 2 diabetic patients with vitamin D deficiency

Tekin Bahar , Bayram F. Buket , Yavuz Dilek Gogas

Aim: There is strong evidence regarding vitamin D being a risk factor for Type 2 Diabetes Mellitus (T2DM). In this study, we aimed to investigate the effects of vitamin D on advanced glycation end-products in prediabetic and type 2 diabetic patients with vitamin D deficiency.Methods: Forty type 2 diabetic patients, 40 prediabetic patients and 40 healthy controls with the levels of vitamin D <20 ng/ml were included in the study. All three groups were ...

ea0041ep872 | Pituitary - Clinical | ECE2016

Endocrinologic outcomes of gamma knife radiosurgery for acromegaly: from an endocrine clinic

Uygur Meliha Melin , Deyneli Oguzhan , Yavuz Dilek Gogas

Although surgical resection is the usual initial treatment for patients with acromegaly, it does not always lead to a remission. Gamma knife radiosurgery (GKRS) is an important additional strategy for unresected clinically active pituitary adenomas.Objective: We evaluated retrospectively pituitary hormone status as well as the efficacy of GKRS for patients with acromegaly referred to our tertiary endocrinology clinic. Prognostic factors related to outcom...

ea0041ep888 | Pituitary - Clinical | ECE2016

Evaluation of endothelial function and insulin sensitivity in patients with prolactinoma

Buket Bayram F , Tekin Bahar , Gogas Yavuz Dilek

Objective: Hyperprolactinemia has been reported to be associated with endothelial dysfunction, abnormalities of carbohydrate metabolism and insulin sensitivity. The aim of this study was to evaluate carbohydrate metabolism and endothelial function of our patients in outpatient clinics.Material and methods: In this cross-sectional study, currently or previously treated 87 hyperprolactinemic patients with PRL-secreting adenoma (fifty four with microadenoma...

ea0041ep915 | Pituitary - Clinical | ECE2016

Prolactin measurements improve the diagnostic accuracy of inferior petrosal sinus sampling

Uygur Meliha Melin , Yasar Mehmet , Deyneli Oguzhan , Yavuz Dilek Gogas

Introduction: Inferior petrosal sinus sampling for ACTH is the current gold standard test for the differentiation of pituitary Cushing disease from the ectopic ACTH syndrome. Early studies with İPSS reported a diagnostic sensitive and specificity approaching 100%, additional experience has shown a false negative rate of 1-10%. This has been due to either technical problem with unsuccessful petrosal sinus catheterization or anomalous venous drainage of the pituitary. The ...

ea0070aep832 | Reproductive and Developmental Endocrinology | ECE2020

Male hypogonadism and sarcopenia

Dinçer Yazan Ceyda , Apaydin Tugce , Gogas Yavuz Dilek

Background and aim: Low testosterone levels are known to be associated with unfavorable body composition and testosterone replacement is known to be associated with increased muscle mass and muscle strength. The aim of this cross-sectionalstudy is to evaluate the grip strength, appendicular muscle mass and physical performance and bone mineral densities of hypogonad male patients.Method: 75 hypogonad and 45 healthy control subjects were included in this ...

ea0056p180 | Bone ' Osteoporosis | ECE2018

Evaluation of bone mineral density and vertebral fracture incidence in a group of kidney transplant recipients

Yavuz Dilek Gogas , Kahveci Arzu , Bugdayci Onur , Tuglular Serhan

Kidney transplant patients are prone to metabolic bone diseases. In this descriptive clinical study we aimed to evaluate the incidence of osteopenia osteoporosis, vertebral fractures in our group of renal transplant patients.Methods: Eighty seven patients (25 males and 62 females) aged from 20 to 67 years, who had undergone kidney transplantation 1 to 20 yrs. previously included in the study. Bone mineral densitometry was performed using dual-energy X-ra...

ea0073aep447 | General Endocrinology | ECE2021

Attitudes of physicians towards the guideline-recommended LDL target levels in diabetic dyslipidemia

Naime Afşar Satiş , Yavuz Dilek Gogas

AımThe aim of this study is to investigate the attitude of physicians, who are specialized in internal medicine, endocrinology, nurology and cardiology, on LDL target levels and antilipidemic treatments in Turkey.MethodsThis study outlines attitudes of physicians towards the guideline-recommended LDL target levels in diabetic dyslipidemia. An invitaiton to fill a questionnaire on demographic and professi...

ea0073aep471 | Pituitary and Neuroendocrinology | ECE2021

Association between fibroblast growth factor-21 and carotid intima media thickness in patients with acromegaly

Uygur Meliha Melin , Yavuz Dilek Gogas , Yazici Dilek

İntroductionThe aim of this study was to evaluate the association between fibroblast growth factor-21 (FGF-21) levels and carotid intima media thickness (CIMT) in acromegalic patients in relation to the atherosclerotic complications.Metarials and methodsThe study goroup included 70 acromegalic patients. According to the disease activity, patients cathegorized inti 2 groups: controlled and active acromega...

ea0081p145 | Pituitary and Neuroendocrinology | ECE2022

The role of advanced glycation end products on vertebral fractures in patients with acromegaly

Melin Uygur Meliha , Dereli Yazıcı Dilek , Gogas Yavuz Dilek

Introduction: Acromegalic osteopathy is an emerging complication characterized by high risk for vertebral fractures (VFS), whereas bone mineral density (BMD) may not be useful to predict the risk. Recent studies have reported that increased advenced glycation end products (AGEs) are associated with bone fragility. We aimed to evaluate the relationship between AGEs and VFs in patients with acromegaly.Study design: Cross-sectionalPat...

ea0049ep47 | Adrenal cortex (to include Cushing's) | ECE2017

Effect of adrenal mass lateralization on diagnostic tests in patients with Cushing

Tarcin Ozlem Ustay , Pehlevan Emre , Imre Eren , Uygur Melin , Deyneli Oguzhan , Yavuz Dilek Gogas

The frequency of adrenal masses is increasing in parallel with the progress of the technology. Most of these masses, which are detected by chance, are not functional, and only a part of them are exposed to an excess of hormone. The most common dysfunction in masses with hormonal activity is hypercortisolism. However, the diagnosis of Cushing’s disease is based on more than one test. In this study, we intended to compare the values of screening tests to determine whether t...