Endocrine Abstracts

The purpose of the study: is to assess the quality of life of patients with type 2 diabetes before treatment with hemodialysis using the WHO Brief Questionnaire for the Assessment of Quality of Life (WHOQOL-BREF) and the Hamilton Depression Scale, taking into account the degree of neuromarker S100.Material and methods: We examined in total for the period from January 1, 2018 to January 1, 2021 - 90 patients suffering from type 2 diabetes mellitus with ch...

The purpose of the study: is to study the frequency of postoperative hypopituitarism after transnasal hypophysectomy (THE) in patients with pituitary adenomas.Material and methods: Under our observation there were 24 patients with NFPA, of whom women were 14, men - 10. The average age of patients was 36.4 years. Total of 24 patients were performed for the period from 2016 to 2021 33 surgery in the neurosurgery department., of which THE - 32, 1 - bifronta...

The purpose of the study: Is to research case of re-growth of non-functional giant pituitary adenoma (NFPA) with panhypopituitarysm in 28-years old womanMaterial and research methods: Patient Karimova N, was born in 1994 in Namangan region. Clinical diagnosis: Non-functional giant pituitary adenoma with total variant of growth. Status after transnasal selective adenomphysisectomy (12.04.16). Re-growth of tumor. Second transnasal selective adenomphysisect...

Tashkent Pediatric Medical Institute, department of endocrinology, department of dietology, Center of the Scientific and Clinical Study of Endocrinology, department of neuroendocrinoloy, Ministry of Health of the Republic of Uzbekistan. Republic of Uzbekistan, 100125, Tashkent, Mirzo Ulugbek str. 56. The aim to study the disorder of secretion of growth hormone for women with PCOS by comparison to patients with NFPA.Material and methods: Under our supervi...

The aim: To study the results of researches 35 patients with different pituitary tumours of sellar area, from them men – 17 (48,6%%), women – 18 (51,4%%).Materials and methods: Depending on sizes there are the adenomas of hypophysis, educed on CT/?RI, patients were up-diffused on two groups: the first group of patients is macroadenomas (from 20 to 30 mm) – 17 (48,6%%), and second group of patients – giant – (more than 30 mm) &#15...

Aim: To study the frequency of growth hormone deficiency (GHD) in patients with nonfunctional pituitary tumors (NFPA).Materials and methods: Over a period of 1.0 year, we studied in our department retrospective data of 33 patients with pituitary tumors in terms of CT/MRI imaging and detailed hormonal functional assessment – STH, IGF-1, LH, FSH, ACTH, prolactin, TSH, cortisol, thyroxine. From the patients are 11 – men and 12 women, mean age of p...

Aim: To assess the quality of life of patients with nonfunctional pituitary adenomas (NFPA) and growth hormone deficiency (GHD).Materials and methods: Eighteen GHD patients with non-functional pituitary adenomas (NFPA), (12 F/6 M), aged 35.5±14.4 yr (mean±SD; range 23–58), body mass index (BMI) 28.6±0.6, with a history of adult-onset hypothalamic-pituitary disease, were recruited for the study. The examination included hormonal assess...

Aim of the research: To study the histological structure of nonfunctional pituitary giant adenomas (NFPA)Materials and methods: We observed 11 patients with giant NFPA, among them 5 male and 6 female, mean age 37.8. All patients were undergone surgical treatment by transsphenoidal access in Center of Endocrinology of MoH RU in neurosurgery department during 2014–2015 year.All patients were undergone the spectrum of analyses, i...

Aim of the research: To study special features of pituitary adenoma (PA) clinical manifestation depending on hormonal characteristic and histological structure, and reveal correlation between clinical manifestation and tumor pathology.Materials and methods: Outcomes of surgery in 66 patients with PA were analyzed. Age of patients at surgery was from 18 to 71 years. Mean age of patients – 44 years.According to K. Thapar classif...

Aim of the research – to study the histological structure of non functional pituitary giant adenomas (NFPA).Materials and methods: We observed 17 patients with giant NFPA, among them 5 male and 6 female, mean age 37.8. All patients were undergone surgical treatment by transsphenoidal access in Center of Endocrinology of MoH RU in neurosurgery department during 2019–2020 year. All patients were undergone the spectrum of analyses, including end...