Endocrine Abstracts

Efficacy and Safety of High Dose Testosterone Therapy in Partial Androgen InsensitivityS. Bandyopadhyay, W.A.Watson, C. M.Park, P. Abraham, S. Philip, S. Acharya , J.S. Bevan. Department of Endocrinology, Aberdeen Royal Infirmary, Aberdeen, AB25 2ZN.INTRODUCTION: There have been few reports of the efficacy and safety of high dose androgen therapy in men with partial androgen insensitivity (PAI). We report on the responses of a p...

Introduction: Diabetes is expected to rise from 177 million today to 370 million in 2030. Self care is a crucial to keep the disease under control. Appropriate self care practice can keep the disease under control.Objective: The aim of the study was to find out the self care practice among diabetic patients.Methods: This is a simple descriptive cross-sectional study. A total of 50 respondents, who met eligible criteria were purposi...

We describe seven patients with pituitary apoplexy diagnosed between July 2009 and Oct 2010.Presentation and Management: Five patients presented with sudden onset headache, nausea and vomiting. One developed headache while on carbegoline and other presented with fluctuating level of consciousness.All but two patients were inpatients at the hospital when diagnosed and all had MRI scan of pituitary to confirm the diagnosis and any ma...

Introduction: High testosterone level lowers the seizure threshold in patients previously well controlled on medication.Clinical scenario: A 59-year-old male, with a history of complex partial seizure, having 12 years of seizure free period on phenytoin and lamotrigine, presented with short history of vomiting, positional headache, and visual impairment. A diagnosis of pitutary macro adenoma was made following a MRI scan of his head. He underwent a trans...

Diabetes is expected to rise from 177 million today to 370 million in 2030. Self care is a crucial to keep the disease under control. Appropriate self care practice can keep the disease under control.The aim of the study was to find out the self care practice among diabetic patients.This is a simple descriptive cross-sectional study was done in Metropolyclinic Kathmandu, Nepal. A total of 50 respondents, who met eligible criteria w...

Introduction: The correlation between lipid profile changes & overt hypothyroidism is well established. Overt hypothyroidism is associated with increased risk for cardiovascular disease (CVD) as indicated by hypertension, elevated lipids levels, hypercholesterolemia, and particularly increased low-density lipoprotein cholesterol (LDL-C) levels. However, lipid profile alterations in primary and subclinical hypothyroidism are controversial. There are hardly any studies from ...

Introduction: Meningitis is a recognized complication of the treatment of pituitary adenoma. It is usually considered as a peri-operative problem but does need to be considered as a potential complication at other points in the treatment pathway. We present two patients with meningitis where the link to pituitary pathology was originally unrecognized.Case report:Patient 2: 41 years old lady, presented with a history of nasal drip u...

Androgen excess in post-menopausal women usually results from ovarian or adrenal pathology. Identifying pathology is significant as many ovarian tumors can be malignant in nature. We report a case of granulosa cell tumor which presented with virilizing signs. A 66-year-old postmenopausal lady presented with temporal hair loss and weight gain. She had to drop out of her church choir as she had a change in her voice. She was concerned about her facial hair growth which was signi...

Introduction: Gastrinoma is a rare neuroendocrine tumor and associated with liver metastasis in 20–40% of cases. We present a rare case report of a patient with stable liver metastasis due to gastrinoma for more than 35 years.Case report: A 49 year old male is currently on our regular clinic follow up for the liver metastasis due to gastrinoma. His past history includes open laparotomy and resection of gastrinoma (Proven histologically) at the age o...

Cerebral salt wasting (CSW) occurs as the result of injury to the central nervous system and is most commonly found among those who have experienced a traumatic brain injury (TBI). Although incidence is varied, it has been reported to be as high as 30% within the patient population presenting to hospital with a TBI. CSW causes hyponatremia with concurrent hypovolemia and increased sodium within urine despite normal renal function. Because of its rare nature, CSW is often misdi...