Endocrine Abstracts

41 year old male presented in 1992 with 2 years history of blurring of vision, headaches, dizzy spells. Had Right supratemporal visual field defect, pituitary MRI which showed cystic pituitary lesion. Had TSS in May 1992 and histology showed Rathkes pouch cyst. Post operatively developed DI and started on DDAVP.SST,TRH and GnRH tests were normal. Persisted retro orbital head aches, developed nasal and temporal field loss. MRI in Sept 1992 showed large intrasellar recurrence of...

Fasting blood glucose is key to diagnosing diabetes, whilst the Oral Glucose Tolerance Test (OGTT) is a valuable adjunct when diagnosis is borderline or inconclusive. The OGTT is often used to detect early changes in glucose tolerance and predict a likely path to overt Diabetes Mellitus for example in gestational diabetes.A 42 year old female, referred to the Endocrine services for episodes of symptomatic hypoglycaemia. Past medical history included pylo...

Background: Neuroendocrine Tumor (NET) patients are the fastest growing population of cancer patients, hence we wanted to assess if there are gaps in patient knowledge and awareness of their disease. To improve our understanding of the factors affecting patient knowledgeability, we looked at their educational level, satisfaction with educational materials provided at initial diagnosis, other sources used for awareness, and their level of accessibility to education materials ab...

Background: Neuroendocrine tumors are a rare group of cancers. The median overall survival of these patients is ~10 years, presenting a unique issue of accrued financial distress over a long period of time. We attempted to look at the potential determinants of financial distress in NET patients, focusing on their demographics, comorbidity burden, educational status and tumor symptoms.Methods: A total of 155 patients have been enrolled in the Roswell Park...

Introduction: Congenital adrenal hyperplasia (CAH) is an inherited disorder, most commonly caused by enzymatic deficiency of 21-hydroxylase (CYP21A2). The non-classic or late-onset form is one of the most common autosomal recessive diseases in women, but the diagnosis is only rarely made in men unless they happen to present with testicular or adrenal masses or infertility.Case report: A 65-year-old man presented with recurrent episodes of postural dizzin...

Historically, acute neurosurgical decompression has been considered treatment of choice for pituitary apoplexy with some studies advocating a conservative approach. We describe a patient, with reduced consciousness due to apoplexy of a gonadotroph adenoma, in whom there was spontaneous tumour shrinkage. A 68-year-old gentleman presented following a collapse with hypothermia, bradycardia and bitemporal hemianopia. Initial investigations showed low plasma sodium and glucose. Ove...