Searchable abstracts of presentations at key conferences in endocrinology

ea0022p24 | Adrenal | ECE2010

Two cousins with 17-α hydroxylase enzyme deficiency

Ozsan Muge , Akarsu Ersin , Aktaran Sebnem , Araz Mustafa

We present two cases because 17OHD is the rare cause of congenital adrenal hyperplasia (1%) and our patients are first cousins (their fathers are brothers). Genetically female patients with congenital adrenal hyperplasia due to 17-α hydroxylase enzyme deficiency (17OHD) represent with sexual infantilism, hypertension and genetically male patients represent with male pseudohermaphroditisim, hypertension at pubertal age. The cousins applied for primer amenorrhea and hyperte...

ea0016p200 | Diabetes and cardiovascular diseases | ECE2008

Relationship between nerve conduction velocity with uncoupling protein 2 promoter polymorphism -866G/A and A allele frequency in type 2 diabetic patients with diabetic peripheral neuropathy

Aktaran Sebnem , Akarsu Ersin , Akcali Aylin Hengirmen , Oguzkan Sibel

Progression of the diabetic peripheral neuropathy (DPN) demonstrated differences in the individual considered the contribution of genetic predisposition. We aim to study the relationship between the −866G/A polymorphism in the promoter region of the uncoupling protein 2 (UCP2) which enhances transcriptional activity and A allele frequency with nerve conduction velocities (NCV) and clinical factors. We compared 370 type 2 diabetic patients with healthy control. Subjective...

ea0090p319 | Calcium and Bone | ECE2023

Unexpected first finding in primary hyperparathyroidism; peripheral giant cell granuloma in the mandibula

Koroğlu İpek , Abidin Sayıner Zeynel , Aytekin Alper , Akarsu Ersin

Aim and Introduction: Peripheral giant cell granulomas (PHDG) are uncommon exophytic lesions of the oral cavity that originate from the periosteum or periodontal membrane as a polypoid mass. Mandibular involvement is more common than maxillary involvement. Patients with primary hyperparathyroidism can infrequently exhibit PHDG in the early stages of the disease. We wanted to present our case who was examined for giant cell granuloma developing in the mandibula and was found to...

ea0049ep1003 | Pituitary - Clinical | ECE2017

Acromegaly: clinical experience and determinants of remission

Eraydin Ayten , Akarsu Ersin , Sayiner Zeynel A , Ozkaya Mesut , Erkutlu Ibrahim , Tabur Suzan , Araz Mustafa

Introduction: Acromegaly is a chronical and rare disease which is accompanied by excessive growth hormone (GH) secreting hypohysis tumor. In this study we presented acromegaly patients’ datas who admitted to our center between the years 1998–2016. We discussed patients’ charecteristics and we aimed to investigate the determinants which is effecting the remission rate of the patients’.Method: 70 acromegaly patients datas were analyzed ...

ea0041gp166 | Pituitary - Clinical (1) | ECE2016

Auditory changes in acromegaly

Tabur Suzan , Korkmaz Hakan , Baysal Elif , Hatipoglu Esra , Aytac Ismail , Akarsu Ersin

Introduction: Certain sensory system functions are affected somehow in acromegaly, however auditory complications have not been identified in detail yet. It is possible that widespread changes in acromegaly may also affect auditory system. We aimed to determine the changes involving auditory system in cases with acromegaly.Methods/design: Otological examination of 41 cases with acromegaly (active n=22, inactive n=19) were compared with ...

ea0037ep1060 | Thyroid (non-cancer) | ECE2015

Paraoxonase and arylesterase levels in autoimmune thyroid diseases

Korkmaz Hakan , Tabur Suzan , Ozkaya Mesut , Oguz Elif , Aksoy Nurten , Akarsu Ersin

Objective: The aim of this study was to evaluate paraoxonase-1 (PON1) activities and its association with oxidative stress status in autoimmune thyroid disease (AITD).Materials and methods: Patients with 25 Hashimoto thyroiditis (HT) and 25 Graves’ disease (GD) and 27 healthy controls were enrolled in the study. Blood samples were obtained in euthyroid period and 3 months after the initiation of medical treatment. ...

ea0026p463 | Thyroid cancer | ECE2011

Comparison of clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma

Akarsu Ersin , Metin Sevim Mehmet , Ozsan Muge , Erkilic Suna , Araz Mustafa

Papillary thyroid carcinoma (PTC) is most frequent endocrine cancer on the other hand papillary microcarcinoma can be seen increasing frequency in recent years. In this study we compare clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma retrospectively.Eighty one PTC and 38 PMC total 119 patients followed between 2005 and 2009 were enrolled study. Average follow-up time is 35 months in PTC a...

ea0090p488 | Thyroid | ECE2023

Evaluation of Factors Determining Iodine Refractoriness in Thyroid Carcinoma

Erten Aslı , Abidin Sayıner Zeynel , Koroğlu İpek , Oğuzkan Balcı Sibel , Akarsu Ersin

Introduction: Radioiodine-resistant thyroid carcinoma is an important milestone in the treatment and follow-up of thyroid cancers. The biological defects of iodine uptake in thyroid cancer cells should be well known. In this study, we aimed to evaluate the clinical and pathological features and SLC5A5 gene expression status of iodine-refractory papillary thyroid carcinoma patients. Material-Method: We studied SLC5A5 expression in 83 papillary thyroid car...

ea0090p530 | Thyroid | ECE2023

Coexistence of thyroid nodule and Graves’ disease: Is it a favorable factor for papillary thyroid cancer?

Yatkın Keleş Yağmur , Abidin Sayıner Zeynel , Koroğlu İpek , ozturk sadettin , Akarsu Ersin

Introduction: The incidence of papillary thyroid cancer (PTC) in the coexistence of Graves’ disease (GD) and thyroid nodule is not known clearly, and the pathophysiology of PTC development in these patients is still unclear. Aim: The aim of our study is to compare the clinicopathological features of GD patients with thyroid nodule + PTC and patients with euthyroid and non auto-immune thyroid nodule + PTC and investigate the clinicopathological featu...

ea0037ep880 | Thyroid cancer | ECE2015

A pitfall of thyroid fine-needle aspiration biopsy results

Ozmen Sevilay , Calik Ilknur , Akarsu Emre , Timur Ozge , Carlioglu Ayse , Sevimli Hakan , Durmaz Senay Arikan , Kurt Ali

Introduction and aim: Bethesda system for thyroid cytopathology has been widely used recently. Approximately 3–7% of thyroid fine-needle aspiration (FNA) biopsy is considered as malign. Suspicious or malign nodules should likely to be resected. Aim of this study is to confirm the diagnosis of malign or suspicious for malignity according to Bethesda classification in patients with nodular goitre after thyroidectomy.Materials and methods: Results of F...