Searchable abstracts of presentations at key conferences in endocrinology

ea0029p665 | Diabetes | ICEECE2012

Relationship Between HbA1c and Asymptomatic Coronary Artery Disease in Type 2 Diabetes Patients

Dundua M. , Akhobadze T. , Kurashvili R. , Kopaleishvili A.

Background: Patients with type 2 diabetes mellitus (T2DM) have elevated risk of coronary artery disease (CAD) development. In this population CAD often proceedsasymptomatically, especially if cardiac autonomic neuropathy (CAN) is present. Our aim was to assess relation between glycemia control and asymptomatic CAD inT2DM pts. Materials and methods: Participants were 160 T2DM patients without documented CAD divided into four groups (Gr.) according to HbA1c levels: Gr. 1 -HbA1c6...

ea0070aep517 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Prevalence of peripheral and cardiac autonomic neuropathy in hypertensive pre-diabetic georgian patients by Sudoscan

Kopaleishvili Ana , Kurashvili Ramaz , Akhobadze Tinatin , Asatiani Natalia , Shelestova Elena

Background: Sudomotor function is used to assessperipheral autonomic system. Electrochemical Skin Conductancemeasurement using electrochemical reaction betweenchloride ions in sweat and stainless steel plate electrodes is a simple, non-invasive and quick method. Several factors, including age, sex, BMI, glycemic status influence sweat function.Aim: Our aim was to determineprevalence of peripheral (DPN) and cardiac autonomic neuropathy (CAN) in hypertensi...

ea0029p621 | Diabetes | ICEECE2012

Complex ventricular arrhythmias with early repolarization in type 2 diabetes mellitus

Kopaleishvili A. , Akhobadze T. , Kurashvili R. , Dundua M. , Inashvili E.

Background and aims: Mortality rate from cardiovascular disease (CV) including sudden death (SD) is pronounced in type 2 diabetic (T2DM) patients with cardiac autonomic neuropathy (CAN) and/or complex ventricular arrhythmias (CVA). Early repolarization (ER) is also considered to be a significant risk factor for SD. The aim of the study was to evaluation the relation between CAN, CVA and ER in T2DM patients.Materials and methods: Participants were 44 T2DM...

ea0029p656 | Diabetes | ICEECE2012

Risk Factors and Therapeutic Management of type 2 Diabetes in Georgia

Akhobadze T. , Kurashvili R. , Paghava K. , Avazashvili M.

Background and aims: Cardiovascular disease (CVD) is a leading causes of death in type 2 diabetes mellitus (T2DM), thus prevention of CVD is of utmost importance. Our aim was to determine whether the ESC/EASD guidelines on CVD prevention in T2DM patients are followed in clinical practice in Georgia.Materials and methods: In total, 824 T2DM patients (age <80 yrs) with no history of coronary or other atherosclerotic disease, who entered Georgian Diabet...

ea0070ep127 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Hyperuricemia in type 2 diabetes patients with atherosclerotic cardiovascular diseases.

Akhobadze Tinatin , Kurashvili Ramaz , Kopaleishvili Ana , Shelestova Elena , Nikachadze Ana , Moistsrapishvili Maka

Background: Studies show relationship between serum uric acid (SUA) and such diseases as type 2 diabetes (T2DM), hypertension (HT) and atherosclerotic cardiovascular disease (ASCVD). There is relationship both in hyperuricemia (HU), and high–normal values of SUA. Significance of this association is unknown; there are controversial data concerning HU role in patients with T2DM/CVD. The aim of the study was to assess SUA in T2DM patients with ASCVD.<...

ea0016p250 | Diabetes and cardiovascular diseases | ECE2008

Nebivolol in diabetic patients with chronic heart failure

Akhobadze Tinatin , Kurashvili Ramaz , Tsutskiridze Liana , Shelestova Elena , Dundua Mzia , Dzneladze Lela

Background and aims: The aim of this study was to study the effect of Nebivolol on clinical course and heart rate variability (HRV) parameters in type 2 diabetes (T2DM) patients (pts) with coronary heart disease (CHD) and Chronic heart failure (CHF) of III-IV FC.Materials and methods: Participants were 35 T2DM pts with CHD and CHF/ III-IV FC. The pts were divided into 2 groups (Gr.) Gr.1 (n=15, 10m/5f, mean age 59±7 years) on basic therapy. G...

ea0011p425 | Diabetes, metabolism and cardiovascular | ECE2006

Effect of lacidipine on left ventricular mass and blood pressure circadian rhythm in hypertensive diabetic patients

Akhobadze T , Kurashvili R , Khelashvili M , Tsutskiridze L , Shelestova E , Dundua M , Paghava K , Kajaia T , Khidesheli T

Background: Impaired circadian blood pressure (BP) variation is a frequent phenomenon in hypertensive type 2 diabetic (T2DM) patients (pts), and is considered a risk factor for development of cardiovascular complication. The aim - to assess the effect of Lacidipine on left ventricular mass (LVM) and BP in hypertensive T2DM pts.Materials and methods: Totally 32 T2DM pts with mild-to-moderate hypertension (20 m/12 f, mean age 57±9.6 yrs) were allocate...