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ea0011p514 | Endocrine tumours and neoplasia | ECE2006

Surgical cure with preserved pituitary function is rare in acromegalic patients. Results from the Preoperative Octreotide Treatment of Acromegaly (POTA) study

Carlsen SM , Schreiner T , Anderud S , Johannesen Ø , Svartberg J , Bollerslev J

Background: In many acromegalics neurosurgery is unable to control GH secretion while it may harm the normal pituitary.Objective: To investigate the effect of pre-treatment with octreotide on surgical outcome in acromegaly.Methods: Previously untreated acromegalics were randomised directly to surgery or octreotide for six month before transsphenoidal surgery. Three months postoperatively patients underwent OGTT and Insulin Toleranc...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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