Searchable abstracts of presentations at key conferences in endocrinology

ea0063p262 | Pituitary and Neuroendocrinology 1 | ECE2019

Rare lesions of sellar, parasellar and suprasellar pathologies

Apaydin Melda , Oruk Guzide Gonca

Differential diagnoses of sellar, parasellar and suprasellar pathologies other than tumors such as common adenoma, rathke cleft cysts and meningioma and craniopharyngiomas were presented. This retrospective study was performed including 25 patients who were operated or treated medically in between 2008 and 2019. The patients were analyzed with preoperative/postoperative magnetic resonance imaging (MRI), endocrinological and neuro-ophthalmologic examination results. Pre and pos...

ea0056p818 | Pituitary - Clinical | ECE2018

Diabetes insipidus due to hypothalamitis and infundibulo-neurohypophysitis

Oruk G Gonca , Apaydin Melda

Autoimmune hypothalamitis has been implicated in idiopathic central diabetes insipidus (DI) due to antibodies against vasopressin producing hypothalamic cells. Lymphocytic infiltration of hypothalamus has been reported in patients with lymphocytic hypophysitis (LH) manifesting as hypopituitarism with DI. These patients can also have other associated autoimmune diseases. Here, we report a case of a male patient who presented with headache, poor orientation, partial hypopituitar...

ea0073aep331 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Do metabolic syndrome and diabetes affect skin autofluorescence in patients with morbid obesity?

Apaydin Tugce , Yavuz Dilek Gogas

PurposeObesity, diabetes mellitus, and metabolic syndrome (MetS) have been known to be associated with increased skin autofluorescence (SAF). In patients with MetS, higher SAF measurements were found to be associated with an increased number of the components of MetS. In this cross-sectional study, we aimed to evaluate the association of MetS and its’ components with skin autofluorescence in severely obese patients and to examine whether diabetes or...

ea0070aep949 | Thyroid | ECE2020

Medullary thyroid cancer follow-up in a tertiary center

Apaydin Tugce , Imre Eren , Gogas Yavuz Dilek

Introduction: Although medullary thyroid cancer (MTC) constitutes 2–4% of all thyroid cancers, it is associated with higher mortality compared to differentiated thyroid carcinomas. Here we present long term clinical results of medullary carcinoma patients’ follow-up in our center.Methods and results: MTC was detected in 27 (3.73%) patients of 850 thyroid cancer cases who were followed-up between 2004 and 2020 at the Marmara University School ...

ea0049ep964 | Pituitary - Clinical | ECE2017

Pregnancy in Cushing’s disease after treatment with surgery and cyber-knife radiosurgery

Oruk G Gonca , Olmezoglu Ali , Apaydin Melda , Guvenc Gonul

Women affected by Cushing’s disease (CD) are often infertile due to abnormal follicular development or anovulation. In these patients, first line treatment is pituitary surgery, which is effective in more than 83% of cases with microadenomas, but only in about 35% of those with macroadenomas. When surgery do not normalize circulating ACTH and cortisol concentrations, such drugs, e.g. ketoconazole or metirapone, and radiotherapy are used as adjuvant treatment. Concerning r...

ea0037ep925 | Thyroid (non-cancer) | ECE2015

A case of primary hypothyroidism initially presenting with massive pericardial effusion

Apaydin Mahmut , Beysel Selvihan , Demirci Taner , Cakal Erman , Delibasi Tuncay

Introduction: Although pericardial effusion is a common finding in primary hypothyroidism, massive pericardial effusion or pericardial tamponade are rare. Herein, we describe a newly diagnosed case of primary hypothyroidism initially presenting with massive pericardial effusion.Case report: A 64 years old male patient attended to the emergency unit with worsening dyspnea over the past 1 month. ECG showed a low voltage QRS wave. Chest X-ray showed increas...

ea0035p863 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Is pregnancy possible with acromegaly?

Oruk Guzide Gonca , Apaydin Melda Arslan , Bahceci Mitat

Acromegaly is usually caused by a GH-secreting pituitary adenoma. Although fertility is frequently impaired, pregnancy can be possible due to improvement in diagnosis and treatment modalities. Tumour enlargement and nontumoral lactotroph enlargement related with pregnancy can compress the optic chiasm and cause visual impairment. Optimal management of acromegaly during pregnancy is not well established. In this paper our experience about the clinical, laboratory, radiologic da...

ea0070aep832 | Reproductive and Developmental Endocrinology | ECE2020

Male hypogonadism and sarcopenia

Dinçer Yazan Ceyda , Apaydin Tugce , Gogas Yavuz Dilek

Background and aim: Low testosterone levels are known to be associated with unfavorable body composition and testosterone replacement is known to be associated with increased muscle mass and muscle strength. The aim of this cross-sectionalstudy is to evaluate the grip strength, appendicular muscle mass and physical performance and bone mineral densities of hypogonad male patients.Method: 75 hypogonad and 45 healthy control subjects were included in this ...

ea0063p271 | Pituitary and Neuroendocrinology 1 | ECE2019

Diverticular perforation of colon: a dangerous complication in Cushing’s disease

Oruk Guzide Gonca , Karakuş Dilek , Eglenoglu Gokce , Pamuk Barış Onder , Apaydin Melda

Exposure to supraphysiologic doses of exogenous glucocorticoids is associated with gastrointestinal (GI) complications such as peptic ulcer disease, gastrointestinal hemorrhage, duodenal ulcer, and colonic diverticular perforation (DP). Patients receiving high dose glucocorticoids, for rheumatological or autoimmune disease are at increased risk for lower gastrointestinal tract abscesses and perforation. However, little is known about GI complications in endogenous hypercortiso...

ea0011p826 | Thyroid | ECE2006

The diagnostic value of doppler ultrasonography in determining the malignancy potential of thyroid nodules

Sahin F , Varer M , Sarsilmaz A , Oruk G , Apaydin M , Uluc E

Objective: It is very important to determine the malignancy risk in thyroid nodules for to improve therapeutic strategies. In this study we attempted to evaluate the relationship of doppler (DUS) and B- mode ultrasonographic (BUS) features of thyroid nodules with fine needle aspiration (FNA) findings.Method: 111 patients which have been followed between March and September 2004 were evaluated with ultrasonography and ultrasound guided FNA was performed i...