Endocrine Abstracts

We investigated 49 patients with non-functioning pituitary macroadenomas: 11 males, 38 females, age 31–78 y.o. (median 61). Extrasellar tumor expansion was observed in 46 (93.9%) patients: suprasellar – 41 (83.7%), laterosellar 27 (55.1%), and infrasellar 18 (36.7%) patients; combined types of extrasellar expansion – 36 (73.5%) patients.Prolactin levels (PRL) varied from 115 to 1495 mU/l, hyperprolactinemia was found in 27 (55.1%) patients...

The aim of the study is to estimate the efficacy of intravenous corticosteroid therapy in patients with active, sever Graves’ ophthalmopathy.Material and methods: 16 patients with bilateral active, sever Graves’ ophthalmopathy were included to the study. Euthyroididsm has been provided, mean dose of methimasol therapy was 9.4±6.6 mg a day, median of TSH- 0.3 mlU/l, median of fT4 –15.3 pmol/l. The median of duration of GO was 6.5 month...

Aim: To estimate influence of radioiodine treatment of Graves’ disease (GD) on course of Graves’ ophthalmopathy (GO).Material and methods: 9 patients with GD and mild or moderate GO were included to the study (3 (33%) men and 6 (67%) women); the anamnesis of smoking had 4 persons (44%). Diagnosis of GO was evaluated by determination of severity and activity of disease with CAS, presents of diplopia, orbital ultrasound. CAS before radioiodine tr...