Endocrine Abstracts

Introduction: Ephrin receptors (EPHs) compose the largest known subfamily of receptors tyrosine kinases and are bound and interact with EPHs-interacting proteins (Ephrins). They have a role in tumor growth, invasion, angiogenesis and metastasis of several neoplasms. Aim of the study was to investigate the expression of EPH-A4, -A5, -B2 and -B5 in pituitary lesions. Material and Methods: Our study group consisted of 18 patients (9 males with median age 54...

Purpose: Pituitary apoplexy is a rare endocrine emergency due to abrupt hemorrhage or infarction of a preexisting pituitary tumor. We aimed to present clinical and biochemical characteristics as well as the management of patients presented with pituitary apoplexy at our department.Methods: Review of the records of all patients presenting with pituitary apoplexy at the Endocrinology department over the last 20 years.Results: During ...

Aims: Although rare, craniopharyngiomas are the commonest suprasellar tumour in childhood. Despite high overall survival, children and young people <19 years with craniopharyngiomas are at risk of multiple relapses and long-term tumour- and treatment-related morbidity. We sought to provide, for the first time, a national standard for best practice based on currently available evidence for the assessment, treatment and follow-up of paediatric craniopharyngiomas under the au...