Searchable abstracts of presentations at key conferences in endocrinology

ea0075m04 | Metabolic Bone | EYES2021

The elderly patients with very high dose vitamin D level: Often present with normocalcemia

Batman Adnan , Altuntas Yuksel

Objective: We aimed to determine the risk of hypercalcemia in a geriatric population with very high dose levels of 25-hydroxy-vitamin D (25(OH)D)Patients and Method: This study was designed as a retrospective, cross-sectional two-center study for examining the elderly patients with very high 25(OH)D levels (>88ng/ml) between January 2014 and December 2019. After recruitment, subgroup analyses of the patients were performed based on their calcium and ...

ea0077oc3.3 | Metabolism, Obesity and Diabetes | SFEBES2021

Sex-specific risk of obesity and cardiometabolic disease in low- and middle-income countries (LMICs): a meta-analysis in 681929 individuals

Melson Eka , Rocha Thais , Zamora Javier , Fernandez-Felix Borja M , Sobhy Soha , Betran Ana Pilar , Arlt Wiebke , Thangaratinam Shakila

Introduction: Obesity is a global health challenge with more than 60% of the world´s population with obesity living in LMICs. Studies have demonstrated that women are more affected by obesity than men. However, the risk of obesity and obesity-related cardiometabolic diseases in women in LMICs have not been documented. The aims of this meta-analysis are: to evaluate the risk of obesity and obesity-related cardiometabolic disease in women compared to men in LMICs and to eva...

ea0073aep332 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Prevalence of obesity and its association with metabolic diseases in women from low-and-middle income countries (LMICs): A systematic review and meta-analysis

Rocha Thais , Melson Eka , Zamora Javier , Borja M. Fernandez-Felix , Soby Soha , Betran Ana Pilar , Arlt Wiebke , Thangaratinam Shakila

IntroductionObesity is a global health challenge, with more than 50% of the world´s obese population residing in LMICs. Although adiposity is a well-known major risk factor for noncommunicable diseases (NCDs) such as hypertension, and diabetes mellitus, the delivery of effective NCDs interventions is still a challenge to health systems. About 85% of the NCDs premature deaths occur in LMICs. Obesity is more prevalent in women than men, however the bu...

ea0037ep760 | Pituitary: clinical | ECE2015

Assessment of mean platelet volume in acromegaly and its relation with disease outcome

Cetinarslan Berrin , Akyay Ozlem Zeynep , Selek Alev , Batman Adnan , Canturk Zeynep , Tarkun Ilhan

Background: Acromegaly is associated with increased risk of coronary atherosclerosis and cardiovascular mortality. Changes in coagulation and fibrinolysis markers in acromegalic patients have been shown to indicate increase in the risk of developing cardiovascular disease. Mean platelet volume (MPV) is a marker of platelet functions and activity, and increased MPV is an independent risk factor of myocardial infarction and thrombotic events. In this study, we examined the level...

ea0037ep761 | Pituitary: clinical | ECE2015

A rare case of papillary thyroid cancer: pituitary metastasis

Akyay Ozlem Zeynep , Cetinarslan Berrin , Tarkun Ilhan , Canturk Zeynep , Selek Alev , Batman Adnan

Introduction: Differentiated thyroid carcinoma (DTC) rarely represents with distant organ metastasis. Cerebral metastasis is seen in 0.4–1.2% of patients with distant organ metastasis. There are only 14 patients of DTC with pituitary metastasis reported in the literature. Here, we report a papillary thyroid carcinoma (PTC) patient represented with pituitary metastasis.Case: A 68-year-old male patient has admitted to our hospital with a growing tumou...

ea0063p878 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Metabolic profile of non-functional adrenal adenomas

Batman Adnan , Yener Ozturk Feyza , Masum Canat Muhammed , Erol Rumeysa Selvinaz , Sen Esra Cil , Yıldız Duygu , Altuntas Yuksel

Aim: Metabolic syndrome rates have been studied especially in adrenal gland secreting cortisol and studies on nonfunctional adenomas are limited. In this study, we investigated metabolic parameters and metabolic syndrome frequency in non-functional adrenal adenomas (NFA).Materials and methods: In our study, 55 patients (15 men (27.3%), 40 women (72.7%) who were diagnosed incidentally, unilateral or bilateral localized, hormone-inactive, and with adenoma-...

ea0049ep109 | Clinical case reports - Pituitary/Adrenal | ECE2017

Prolonged zona glomerulosa insuffiency with hyperkalemia in primary hyperaldosteronism after adrenalectomy

Ozturk Feyza Yener , Sen Esra Cil , Erol Rumeysa Selvinaz , Saygili Emre Sedar , Basmaz Seda Erem , Cakir Sezin Dogan , Batman Adnan , Altuntas Yuksel

Introduction: Hyperkalemia due to zona glomerulosa (ZG) insufficiency is generally transient and mild for patients with aldosterone-producing adenoma (APA) after adrenalectomy. We report here a case with prolonged ZG insuffiency requiring long-term mineralocorticoid replacement (MR) therapy.Case report: A 45-years-old female with hypertension and hypokalemia admitted to outpatient clinic with incidentally detected right adrenal adenoma (3 cm) showing sig...

ea0049ep836 | Clinical case reports - Pituitary/Adrenal | ECE2017

Successful management of macroprolactinoma with aromatase inhibitor in a patient with hypogonadotropic hypogonadism

Ozturk Feyza Yener , Sen Esra Cil , Erol R Selvinaz , Cakir Sezin Dogan , Basmaz Seda Erem , Saygili Emre Sedar , Batman Adnan , Altuntas Yuksel

Introduction: Hypogonadism persisting in man with macroprolactinoma requires exogenous testosterone replacement therapy (TRT). But TRT may cause secondary elevations of prolactin. We report here a case of macroprolactinoma and hypogonadotropic hypogonadism with persistently high prolactin level after initiating TRT.Case report: A 28 year-old male was admitted to outpatient clinic with complaints of headache, low libido and blurred vision on left eye for ...

ea0056gp191 | Pituitary / Growth Hormone ' IGF Axis | ECE2018

Ectopic Cushing’s syndrome secondary to medullary thyroid carcinoma with apparent signs of hypercortisolism: a case report

Canat M Masum , Cakir Sezin Dogan , Yildiz Duygu , Ozturk Feyza Yener , Erol Rumeysa Selvinaz , Sen Esra Cil , Saygili Emre Sedar , Basmaz Seda Erem , Batman Adnan , Altuntas Yuksel

Introduction: Ectopic ACTH syndrome (EAS) is a rare cause of Cushing’s syndrome. EAS is most frequently caused by bronchial carcinoid tumor or small cell lung cancer. Medullary thyroid carcinoma (MTC) is a rare source of EAS, as reported in this case.Case report: A 65-years-old-female with back pain and weight gain referred to our outpatient clinic with determined signs and symptoms of hypercortisolism. She had arterial hypertension, her sister had ...