Searchable abstracts of presentations at key conferences in endocrinology

ea0011p820 | Thyroid | ECE2006

Application of positron emission tomography (PET) in the study of cerebral glucose uptake in hypothyroid rats: effect of T3 administration

De Servi M , Belcari N , Bernal J , Refetoff S , Salvadori P , Gianetti E , De Marco G , Tonacchera M , Vitti P , Del Guerra A , Pinchera A

Thyroid hormone (TH) plays a major role in nervous system development. Its deficiency causes severe brain malfunction, which in the human results in cretinism. With the recent availability of new imaging techniques, as small animal PET, it is now possible to study cerebral metabolism in vivo. The aim of this work was to study the in vivo effect of TH on the brain of hypothyroid rats in terms of metabolic function, using PET scanning. For the experiment we used th...