Endocrine Abstracts

Introduction: Asthma is often associated with various comorbidities, which may affect its clinical intensity and severity. The mechanisms of adult–onset asthma may include several metabolic and inflammatory components that are common to the other diseases such as obesity, metabolic syndrome, type 2 diabetes mellitus (T2DM), cardiovascular diseases and psychiatric diseases.Objectives: Assessment of asthma symptom control and QoL in a subgroup of ast...

Aging is associated with weight loss, appetite decline, reduced fat-free mass (FFM) and increased fat mass (FM). Dysregulation of the ghrelin and leptin systems could reduce hunger and promote early satiety in elderly subjects, leading to impairment of the nutritional status. To better clarify this issue, we evaluated the response of plasma ghrelin and leptin to a standardised oral mixed nutrient load (SOMNL) in elderly subjects with different body composition. The study popul...

Thyroid Associated Ophtalmopathy (TAO) is considered one of the most difficult pathologies to treat and a big threat for Graves Disease (GD) patients. This has enhanced the interest in finding a marker that can predict the onset and the prognosis of TAO. It has been demonstrated that GD is a chronic inflamed tissue that there is a remodelling of the ECM structure which elaborate inflammatory signals itself and also promotes the recruitment of cells from the bloodstream; these ...