Searchable abstracts of presentations at key conferences in endocrinology

ea0002sp4biog | Society for Endocrinology Jubilee Medal Lecture | SFE2001

Society for Endocrinology Jubilee Medal Lecture

Besser M

Michael Besser, St Bartholomew's and Royal London School of Medicine and Dentistry, London, UK AbstractProfessor Michael Besser qualified in medicine in 1960 at the Medical School of St Bartholomew's Hospital, and then undertook a number of junior medical posts there and at the Royal Postgraduate Medical School and the Royal Brompton Hospital. He started his academic work initially as junior lecturer in therapeutics i...

ea0066d1.1 | (1) | BSPED2019

Besser Rachel

Dr Rachel Besser BSc MBBS (Hons) MRCPCH PhD, is a consultant in paediatric endocrinology at Oxford Children’s Hospital, and Honorary senior clinical lecturer at the University of Oxford, working with both the NIHR Oxford Biomedical Research Centre and the Wellcome Centre for Human Genetics. She came to Oxford in 2016 and was Clinical Lead between 2016–2018, and is now Research and Audit lead for the department. Rachel splits her job between clinical diabetes and diab...

ea0036cme6 | CME Session | BSPED2014

Trainees update

Besser Rachel , Steele Caroline

The trainee reps (Drs C Steele and R Besser) will provide an update on their activities on behalf of the trainees in the past year including:i) Update of the trainees’ section of the BSPED website.ii) Results of a recent survey of GRID trainees aimed to track training and for future workforce planning.iii) Ongoing activities (such as trainees’ section of the BSPED newsletter) and number of e-mail co...

ea0078dpd3.2 | Session 2 (1) | BSPED2021

100 years of insulin - is it time for a UK Type 1 diabetes screening strategy?’

Besser Rachel

2021 is an important year for diabetes. It is 100 years since insulin was discovered and the first child had their life saved by insulin, turning a death sentence into a chronic condition. Since then, insulin has remained the mainstay of treatment for type 1 diabetes. Outcomes have improved with advances in technology, but outcomes remain suboptimal and, in the UK, around 25% children still present late, in a state of life-threatening diabetic ketoacidosis (DKA). DKA rates hav...

ea0002sp4 | Society for Endocrinology Jubilee Medal Lecture | SFE2001

Recent studies in normal and abnormal growth hormone secretion

Besser G

The nature of the hypothalamic factors which control GH secretion in animals and man have emerged since the description of somatostatin (SS) in the early 1970s. Confusion originally arose when the ubiquitous distribution and apparent non-specificity of the actions of SS were established. Understanding of the paracrine nature of SS's action and the dependence of the specificity of its effects upon the locus of secretion and its short half-life in the circulation provided for an...

ea0095ds1.1 | Diabetes Symposium 1 | BSPED2023

Preparing for a softer landing at diagnosis - how to manage a child with pre-T1D

Besser Rachel

Type 1 diabetes (T1D) can be identified pre-symptomatically, by measuring islet associated autoantibodies (IAb). In an analysis from multiple prospective cohort studies, >80% children with two or more IAbs developed clinical T1D over 15 years of follow up. The reasons for identifying children presymptomatically include reducing the risk of diabetic ketoacidosis at diagnosis and the related morbidity and mortality, reducing the need for hospitalisation, providing time to al...

ea0095p24 | Diabetes 1 | BSPED2023

A UK survey on the screening and management of childhood pre-clinical type 1 diabetes

Swaby Rabbi , Randell Tabitha , Scudder Claire , Bowen-Morris Jane , Townson Julia , Dayan Colin , Marcovecchio Loredana , Besser Rachel

Introduction: Type 1 diabetes (T1D) onset may start years prior to clinical presentation. Screening children and young people (CYP) for T1D using islet autoantibodies (IAb) through research studies is gaining international momentum, since screening reduces diabetic ketoacidosis, hospitalisation and offers access to drug therapies for delaying T1D onset1. Recently, ISPAD provided recommendations on monitoring for pre-clinical T1D in CYP, however no U...

ea0090ep279 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Footwear in a population of diabetic patients

Elarem Soumaya , Dorgham Imen , Salah Aymen Haj , Krifa Bessem , Feni Nedra , Sghir Mouna , Kessomtini Wassia

Introduction: Diabetic foot is one of the major complications of diabetes. Footwear has been found to be a precipitating cause of injury leading to lower extremity ulceration and amputation in people with diabetes. The aim of this study was to determine the suitability of footwear in a population of diabetic patients.Methods: A cross sectional study including 150 patients with diabetes mellitus was conducted. Patients were asked about their follow-up dur...

ea0066p26 | Diabetes 2 | BSPED2019

Two cases of bilateral cataracts in early type 1 diabetes

Lelliott Alice , Basu Supriyo , Besser Rachel

Introduction: Cataract development as a complication of diabetes is usually associated with increased age and longer duration of diabetes. However, rapidly progressive cataracts have also been described at, or soon after, diagnosis of type 1 diabetes (T1DM). We report two cases of adolescents with T1DM and bilateral cataracts, including one case in which visual loss was the presenting symptom.Cases: A 16-year old non-obese, caucasian boy presented to his...

ea0051p086 | Diabetes | BSPED2017

Short-term use of the flash glucose monitoring system increases insulin bolusing and self-confidence in paediatric Type 1 diabetes

Yardley Diana , Basu Supriyo , Besser Rachel Elizabeth Jane

Introduction: The Flash glucose monitoring system (FGS) has recently received a licence for children and young people aged 4–17 years with Type 1 diabetes (T1D) in the United Kingdom. Although many families attending a single UK diabetes centre reporting utilising FGS even prior to its licence we aimed to assess the patient experience.Methods: Patients and families were invited to undertake a 14 day FGS trial following group introductory sessions. 8...