Searchable abstracts of presentations at key conferences in endocrinology

ea0046p12 | (1) | UKINETS2016

Evaluation of a novel microfluidic device for epitope-independent enrichment of circulating tumour cells (CTCs) in patients with neuroendocrine tumours (NET)

Childs Alexa , Kularatne Bihani , Vesely Clare , Ensell Leah , Hartley John , Meyer Tim

Background: The identification and characterization of CTCs as part of a minimally invasive “liquid biopsy” has potential as a real-time biomarker in cancer patients. Using blood samples from NET patients, we evaluate the epitope-independent Parsortix, which enriches CTCs based on size and rigidity, and compare to the EpCAM-dependent CellSearch platform.Methods: About 10 patients with histologically confirmed metastatic NET had synchronous 7.5 ...