Searchable abstracts of presentations at key conferences in endocrinology

ea0011p296 | Diabetes, metabolism and cardiovascular | ECE2006

Biochemical predictors of the cardiovascular complications in patients with obesity and type 2 diabetes

Doliashvili Tamar , Giorgadze Elen , Tsagareli Nana , Asatiani Keteva , Bochorishvili Keteva

Background: The impact of hyperglycemia on atherogenesis is regulated through the increase of the oxidative stress, increase of the rest of the glycosylated products of metabolism and development of the endothelium dysfunction.Aim: To compare the biochemical indexes and investigate their relationship with the development of cardiovascular disease in obese patients with and without type 2 diabetes.Materials and methods: 21 patients ...

ea0011p424 | Diabetes, metabolism and cardiovascular | ECE2006

Left ventricular geometry and contractile ability in type 2 diabetes and non-diabetic patients with mild hypertension

Beridze N , Bochorishvili I , Iashvili M , Kurashvili R , Dundua M

The aim: To reveal relation between altered left ventricular (LV) geometry (G) and contractile ability (CA) in nonbese type 2 diabetic (DM2) patients with mild hypertension (MH).Materials and methods: BP at rest, 24-h ambulatory BP monitoring and echocardiography were investigated in 70 non-obese males, aged 25–50 yrs. They were divided into the following groups: Gr.1, n=15 – DM2 and normal BP, fasting C-peptide (C-p, ng/ml) 4.3±0.9...

ea0011p458 | Endocrine tumours and neoplasia | ECE2006

Carbohydrate metabolism in patients with hypercorticism

Chachibaia Vasil , Korinteli Maka , Giorgadze Elen , Gvadzabia Badri , Bochorishvili Keteva

Aim: To study the carbohydrate metabolism in patients with Itsenko-Kushing’s disease (IKD) and Itsenko-Kushing’s syndrome (IKS).Materials and Methods: 23 patients with hypercorticism were investigated. From which in 8 patients IKD was diagnosed, and in 15 – IKS. In patients with IKD the amount of cortizol was at 8.00 – 273.3±56.8 ng/ml (N- 50–250 ng/ml); 20.00 – 343.3±43.8 ng/ml (N- 50–250 ng/ml); the value of...

ea0020p460 | Obesity and Metabolism | ECE2009

Correlation of leptin, total body fat mass and body fat distribution in overweight postmenopausal women

Dolidze Nino , Giorgadze Ellen , Asatiani Ketevan , Tsagareli Marina , Lomidze Marina , Surmava Arkadi , Bochorishvili Ketevan

We have investigated the leptin production by total and regional fat mass in 32 overweight postmenopausal women as well as the relation between serum leptin levels, total body fat mass and body fat distribution variables. Body mass index (BMI) was calculated in kg/m2. Serum concentrations of leptin were evaluated by RIA. Body composition – trunk/total, arms+legs/total+legs/trunk, android/gynoid ratios were assessed by dual-energy X-ray absorptiometry (DEXA). Th...

ea0014p223 | (1) | ECE2007

The role of nitric oxide in pathogenesis of development of arterial hypertension during obesity

Giorgadze Diana , Giorgadze Ellen , Doliashvili Tamar , Sanikidze Tamar , Asatiani Ketevan , Bochorishvili Ketevan , Surmava Arkadi

Background: The cardiovascular complication is the main cause of morbidity and mortality in obese patients. Endothelial dysfunction and atherosclerosis have the goal role in development of these diseases. The aim of our study was to reveal the role of nitric oxide during obesity associated arterial hypertension.Subject and method: 200 obese patients (age 35–55) were investigated. Control group comprised 25 healthy subjects. We calculated BMI, determ...