Searchable abstracts of presentations at key conferences in endocrinology

ea0029p543 | Diabetes | ICEECE2012

Prevalence of Microalbuminuria in Galicia (NW Spain) and its association with risk factors: Hypertension, Type 2 diabetes mellitus and Pre-diabetes.

Tome M. , Lopez-Raton M. , Botana-Lopez M. , Cadarso-Suarez C.

Introduction: Microalbuminuria tends to appear in Type 2 diabetes (T2D) and reflecting underlying cardiovascular disease rather than diabetic nephropathy presented at diagnosis. The objective of this study was to evaluate the prevalence of microalbuminuria and its possible relations with T2D, pre-diabetes and hypertension, in a representative sample (n=2860) of the adult population (>18 years old) of Galicia (NW Spain).Material and methods: Subjects ...

ea0011p809 | Thyroid | ECE2006

Study of the prevalence and mechanisms of action of TSH receptor and Gs protein alfa-subunit mutations, in toxic multinodular goiter and toxic adenoma from Galicia (Spain)

Palos F , Perez O , Alvarez-Iglesias V , Cameselle J , Barreiro F , Araujo D , Argueso R , Botana M , Cabezas JM , Dominguez L , Martinez T , Nuño J , Rueda JC , Lado-Abeal J

Toxic adenomas (TA) and toxic multinodular goiters (TMNG) are frequent causes of hyperthyroidism in Galicia, an endemic goiter area. In some European countries, 40–80% of toxic goiters are caused by TSH receptor (TSHr) and Gs alfa-subunit (Gsa) mutations that activate cAMP pathway.Aims: To study 1) the prevalence of TSHr and Gsa mutations in TMNG and TA from Galicia, 2) the clonality of sequenced samples, 3) the constitutive activity of the identifi...