Searchable abstracts of presentations at key conferences in endocrinology

ea0022p734 | Steroid metabolism & action | ECE2010

Muscle fiber conduction slowing and decreased levels of circulating muscle proteins after short-term dexamethasone administration in healthy subjects

Lanfranco Fabio , Minetto Marco Alessandro , Botter Alberto , Baldi Matteo Domenico , Motta Giovanna , Ghigo Ezio , Arvat Emanuela

Context: Glucocorticoids are known to decrease protein synthesis and impair membrane excitability of muscle fibres. However, their short-term effects on muscle structure and function of healthy subjects remain poorly understood.Objective: To investigate whether steroid administration could decrease the circulating levels of muscle proteins and modify myoelectric indexes of sarcolemmal excitability and fatigability.Design: Single-bl...

ea0084ps1-03-20 | Thyroid Cancer CLINICAL 1 | ETA2022

Changes in clinical status after second 131I treatment in patients with differentiated thyroid cancer (dtc) not cured with the initial treatment

Gambale Carla , Matrone Antonio , Bottaro Valeria , Prete Alessandro , Faranda Alessio , Contartese Lea , Bianchi Francesca , Torregrossa Liborio , Basolo Fulvio , Molinaro Eleonora , Elisei Rossella

Objectives: Currently 131I treatment after surgery is suggested in selected intermediate-risk and in high-risk patients with DTC. In patients with radio-avid structural disease and in those with biochemical disease a second 131I treatment could be considered. However data about the impact of the second 131I treatment on clinical status remains controversial.Methods: Clinical data of 231 DTC patients followed at the Unit o...

ea0092op-09-05 | Oral Session 9: Thyroid Eye Disease | ETA2023

Clinical and visual outcomes of dysthyroid optic neuropathy after surgical orbital decompression

Armenti Mirco , Curro Nicola , Guastella Claudio , Bottari De Castello Alessandra , Chiara Fazio Maria , Contarino Andrea , Rossi Giada , Muller Ilaria , Arosio Maura , Viola Francesco , Pignataro Lorenzo , Salvi Mario

Objectives: Dysthyroid Optic Neuropathy (DON) is a severe complication of GravesÂ’ Orbitopathy (GO), requiring prompt treatment. First line treatment is high dose intravenous steroids, then surgery is considered mandatory. We studied the clinical outcomes of surgery for DON, with and without previous therapy with steroids.Methods: 88 orbits of 56 patients with DON were treated with surgical orbital decompression. 33 orbits (37.5 %) underwent surgery ...