Endocrine Abstracts

Experimental data demonstrate interactions of steroids with efflux carriers of the multidrug-resistance transporter family (P-glycoprotein, MRP) as well as the poly-specific uptake carriers of the organic anion transporting polypetptide (OATP), organic cation transporter (OCT), and the organic anion transporter (OAT) families in different tissues.P-glycoprotein is associated with glucocorticoid-resistance of many diseases including cancer but also modula...