ea0016p455 | Neuroendocrinology | ECE2008
Ferrau Francesco
, Romanello Giovanni
, Squadrito Stefano
, Carerj Scipione
, Nipote Carmelo
, Iudicello Raffaella
, Trimarchi Francesco
, Cannavo Salvatore
Mortality risk is increased in acromegalics, due to cerebrovascular and cardiovascular events. These events are namely related to atherosclerotic vascular alterations, both at coronary and peripheral level. Systemic comorbidities increase the risk of atherosclerosis, but the role of GH and IGF-1 excess is still debated. To evaluate the relationship between GH/IGF-1 excess, systemic atherogenic complications and vascular alterations we investigated stiffness index (β), pul...