Endocrine Abstracts

Background: Peripheral arterial disease is a disorder due to obstruction of blood supply to extremities. Diabetes mellitus and hypertension are predisposing factors.Objective: To determine if the presence of concurrent hypertension increases the risk of peripheral arterial disease (PAD) in Nigerians with type 2 diabetes.Methods: This was a cross-sectional study that included 160 persons living with diabetes mellitus (60 subjects ha...

Acromegaly is a rare disease that leads to considerable morbidity and mortality, both reversible by adequate control of the disease. However, patients that could be adequately controlled confront delays in achieving treatment targets. The aim of the present study was to estimate the time to disease control after diagnosis and the reason leading to control delays. We retrospectively studied 119 acromegalic patients (aged 46.4±12.5; 71 females). Following appropriate treatm...

Introduction: Adrenal incidentalomas (AI) with or without concomitant autonomous cortisol secretion can be associated with several metabolic alterations that may lead to increased cardiovascular risk. However, data regarding insulin resistance (IR) during long term follow-up of AI are scarce. The aim was to prospectively investigate the presence and evolution of IR in patients with AI between 2003 and 2014.Methods: Seventy three patients with AI for at l...

Introduction: Non-alcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease in the western world affecting 5-33% of the general population. Polycystic ovarian syndrome (PCOS) is a common endocrinopathy affecting 6-10% of women of reproductive age. In both conditions, insulin resistance (IR) seems to be a common pathogenetic mechanism.Objective: To investigate the presence of NAFLD in lean and obese women with and without PCOS ...