Endocrine Abstracts

Introduction: Infants born to mothers on antenatal steroid medication may develop adrenal suppression postnatally which can be potentially life-threatening. However, the incidence is unknown and screening for at risk infants is not universal.Aim: The aim of our study was to review the outcome of infants born to mothers on antenatal steroids.Method: We retrospectively reviewed our neonatal “paediatric alerts” for mothers o...

IntroductionParathyroid crisis (PC) is a very rare yet fatal clinical condition which mandates urgent intervention. We present a case of parathyroid crisis with severe symptomatic hypercalcemia and multi-organ involvement.Case descriptionA 63-year-old male presented with three days of generalized fatigue, abdominal pain and vomiting. Review of systems revealed constipation and symptoms suggestive of depressio...

Introduction: Drug-induced lupus erythematosus (DILE) is a variant of systemic lupus erythematosus that resolves within days to months after withdrawal of the drug, in a patient with no previous history of SLE.Case report: A 60-year-old female presented at Mother Teresa Hospital with toxic multinodular goiter. She received treatment with propylthiouracil and atenolol for a month, and she developed symptoms like malaise, muscle pain, shortness of breath, ...

Introduction: Anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis drugs induced are a rare side effect of antithyroid drugs. It is more commonly associated with propylthiouracil (PTU). The clinical manifestations are polymorphic like in primary vasculitides, but less severe; ranging from less specifics syndromes to multiple organs injured and lifethreatening in rare case. Cardiac involvement is uncommon. Herby we present the first case report of a 25-yr-old wom...

Background: Diabetic ketoacidosis (DKA) has been associated with severe hemolysis in patients with Glucose-6-phosphate dehydrogenase (G6PD) deficiency after restoration of euglycemia. Less than 30 cases have been reported so far. The exact mechanism is not fully understood.Case presentation: A 35-year-old African American man presented to the emergency department with polyuria, polydipsia, abdominal pain and weight loss the last 15 days. Physical examina...

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with multisystem involvement and varied presentation but its association with adrenal insufficiency is rarely reported.Case presentation: A 30-year-old female presented to the emergency department with fever, lethargy and syncopal episodes during the last 48 h. She complained of general weakness, abdominal pain, nausea, vomiting, weight loss and anorexia for five months. Symptoms det...

Introduction: Type B insulin resistance syndrome is an autoimmune disorder characterized by the production of autoantibodies against the insulin receptor. It leads to glucose metabolism disorders, extreme insulin resistance, hyperandrogenism and is associated with other features of autoimmunity.Case report: A 27-year-old man, with a 2-years history of psoriasis, was admitted to our Department because of loss of weight (20 kg in 1 year) and fatigue. He al...