Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep189 | Calcium and Bone | ECE2023

Multiple brown tumors mistaken for bone metastases: Bone scintigraphy and 99m-Tc sestamibi imaging findings

Nasr Maali Ben , El Ajmi Wassim , Sellem Ali , Hammami Hatem

Introduction: Brown tumors or osteitis fibrosa cystica are benign bone tumors complicating uncontrolled primary or secondary hyperparathyroidism. They may behave aggressively and can be destructive. Their osteolytic aspect may be misinterpreted as skeletal metastases.Methods: A 37-year-old female patient with chronic renal failure on dialysis, presented with pain and swelling of her left knee for 10 days, with no associated trauma. She gave history of tu...

ea0081ep103 | Adrenal and Cardiovascular Endocrinology | ECE2022

Metastatic adrenal carcinoma? When not everything is what it seems\..

Rivero Daniel Medina , Gavira Isabel Mateo , Vilchez Lopez Francisco Javier

69-year-old male, with a history of bipolar disorder under treatment, smoker and high blood pressure. He is referred for left adrenal injury detected incidentally by secondary hypertension study. Abdominal CT shows a mass of 67.7×51.8×52.3 mm in the left adrenal area, with radiological characteristics of malignancy and aggressive behavior, contacting the left renal pole and upper splenic pole, compatible with adrenal carcinoma vs. metastasis. The functional study is ...

ea0090ep207 | Calcium and Bone | ECE2023

Primary hyperparathyroidism revealed by multiple brown tumors: A case report

Toulali Fatima , Farah Kamel , Gorgi Khaoula , Isselmo Diehah , Rifai Kaoutar , Hinde Iraqi , Gharbi Mohamedelhassan

Introduction: Primary hyperparathyroidism revealed by multiple brown tumors is rare. We report the case of a patient with primary hyperparathyroidism on parathyroid adenoma discovered in front of multiple brown tumors.Case Presentation: A 72-year-old female patient, who presented for 6 months a functional impotence of both lower limbs with paraparesis, associated with bone pain from where the realization of a phospho-calcium assessment returning in favor...

ea0073ep11 | Adrenal and Cardiovascular Endocrinology | ECE2021

A 14 cm nonfunctioning left adrenocortical carcinoma in an adult man: a case report

jasser Maatougui , Mehdi Raboudi , Besrour Chayma , Chadia Zouaoui , Ramzi Khiari , Haroun Ouertani , Samir Ghozzi

BackgroundAdrenocortical carcinoma is a rare endocrine malignancy, with an unfavorable prognosis. Radical adrenalectomy is the gold standard for localized disease.Case presentationWe report a case of a 47-year-old male with left abdominal pain and sensation of discomfort. Our patient didn’t present classical tumor symptoms, such as cachexia or night sweats. Computed tomography revealed a left heterogeneo...

ea0022p100 | Bone/Calcium | ECE2010

Vitamin D status among adults in the Aegean region of Turkey

Hekimsoy Zeliha , Dinc Gonul , Kafesciler Sabriye , Onur Ece , Guvenc Yesim , Pala Tumer , Guclu Feyzullah , Ozmen Bilgin

Vitamin D is a lipid-soluble hormone found in certain foods and synthesized from precursors in the skin when exposed to ultraviolet light. Vitamin D plays a critical role in bone metabolism and many cellular and immunological processes; and low levels have been associated with several chronic and infectious diseases. Vitamin D status is assessed by measuring the concentration of serum 25-hydroxy vitamin D (25(OH) D). Vitamin D deficiency is reported to be common worldwide, but...

ea0090ep637 | Endocrine-related Cancer | ECE2023

Neuroendocrine carcinoma of the vagina in a young patient – a rare entity

Duta Simona Gabriela , Dumitras Teodor , Sorina Martin Carmen , Cima Luminita , Nitipir Cornelia , Terzea Dana , Fica Simona

Primary vaginal malignancy is uncommon, accounting for about 2% of all gynecological tract cancers, with small-cell neuroendocrine carcinoma of the vagina being exceptionally rare and aggressive. They display similar histological and immunohistochemical features to small-cell carcinomas of different origin. Few cases are reported in the literature so far and therefore, there is no current treatment protocol consensus. We report the case of a 34-year-old nulliparous patient, wh...

ea0090ep932 | Reproductive and Developmental Endocrinology | ECE2023

Multisystemic maccune albright syndrome: what is the management

Amel Rahal

Introduction: Maccune albright syndrome; is a rare disorder resulting from the involvement of several organs; the phenotype is variable depending on the clinical manifestations linked to the importance of the tissues affected by the mutation.Case report: In our patient, the diagnosis was not made until she was 8 years old, despite some suggestive signs: as café au lait skin macules at birth and early forearm bone fractures at the age of 3 years. At ...

ea0063p115 | Calcium and Bone 1 | ECE2019

Severe diffuse tissue calcifications in a patient with pseudohypoparathyroidism type 1 A due to a novel large deletion of GNAS gene

Brancatella Alessandro , Mantovani Giovanna , Marcocci Claudio , Cetani Filomena

Pseudohypoparathyroidism type 1 A (PHP-1A) is a rare genetic disorder characterized by hypocalcemia, hyperphosfatemia, multi hormones resistance (PTH, TSH, Calcitonin, GH) associated with Albright hereditary osteodystrophy (AHO) features. The disease is caused by GNAS haploinsufficiency due to inherited inactivating mutation of GNAS-gene that codes for the stimulatory alfa subunit of G protein. A positive genotype-phenotype correlation was recently hypothesized. The purpose of...

ea0049ep856 | Clinical case reports - Pituitary/Adrenal | ECE2017

Ectopic ACTH syndrome presenting with partial loss of conciousness and nonconvulsive status epilepticus in a patient with no signs of Cushing syndrome

Mert Eray Onur , Yaman Samet , Ozdemir Didem , Bestepe Nagihan , Saglam Dursun Ali , Ersoy Osman , Ersoy Reyhan , Cakir Bekir

Introduction: Ectopic adrenocorticotrophic hormone (ACTH) syndrome is associated with variable tumor groups most commonly originating from neuroendocrine cells. Here, we reported a patient considered to have nonconvulsive status epilepticus initially due to neurological symptoms and diagnosed as neuroendocrine tumor with ectopic ACTH syndrome.Case: A 85 years old woman with regulated hypertension admitted with partial loss of conciousness. She had cachec...

ea0037ep1008 | Thyroid (non-cancer) | ECE2015

Graves' disease with autoimmune haemolytic anemia

Salam Randa , Ramadan Nagwa , Gaber Fatma

Introduction: Haematologic involvement is not uncommon in Graves’ disease. Autoimmune haemolytic anaemia is occasionally reported in patients with other autoimmune illnesses. However very rarely reported in Graves’ disease.Case report: We report a 19-year-old female with reactive arthritis, Graves’ disease and autoimmune haemolytic anaemia while under treatment with methimazole. Physical examination: Under built female BMI 17, Blood pressu...