Searchable abstracts of presentations at key conferences in endocrinology

ea0011oc16 | Steroids and reproductive endocrinology | ECE2006

17β-estradiol regulates pituitary AnxA1 expression and externalization in vivo and in vitro

Davies EL , Christian HC , Omer S , Buckingham JC , Morris JF

Annexin A1 (AnxA1) acts as a mediator of glucocorticoid (GC) actions in neuroendocrine systems. In the anterior pituitary Anx-1 is expressed mainly by folliculostellate (FS) cells and mediates the early-delayed feedback inhibition exerted by GCs on release of ACTH and other pituitary hormones. GC cause the externalization of AnxA1. The stress responsiveness of the female rat hypothalamo-pituitary-adrenal system varies with the estrous cycle, with increased CORT release in resp...

ea0078nep1.2 | Session 1 | BSPED2021

Non-medical prescribing: how can you make a difference to your service as a non-medical prescriber?

Davies Kate

There are more registered Independent Nurse Prescribers than ever before, and with the advent of paediatric specific prescribing courses and more advanced clinical practice degrees, these numbers will certainly increase. The advantages of practising as an independent nurse prescriber can benefit patient care, improve patient safety, and enhance the overall quality of care a patient receives. This presentation will explore these concepts and introduce advanced clinical skills i...

ea0050s11.1 | New developments in adrenal hypertension | SFEBES2017

ACTH: an underappreciated driver of hypertension

Davies Eleanor

Hypertension is one of the most common risk factors for cardiovascular disease and is well known to have a substantial heritable component. The mineralocorticoid aldosterone plays a key role in the regulation of BP and excess production can lead to hypertension. Therefore, much attention has focused on the genes mediating its biosynthesis.The terminal stage of aldosterone production is catalysed by the aldosterone synthase enzyme, encoded by the CYP1...

ea0050s11.1 | New developments in adrenal hypertension | SFEBES2017

ACTH: an underappreciated driver of hypertension

Davies Eleanor

Hypertension is one of the most common risk factors for cardiovascular disease and is well known to have a substantial heritable component. The mineralocorticoid aldosterone plays a key role in the regulation of BP and excess production can lead to hypertension. Therefore, much attention has focused on the genes mediating its biosynthesis.The terminal stage of aldosterone production is catalysed by the aldosterone synthase enzyme, encoded by the CYP1...

ea0044n2.1 | Nurse session 2: Male fertility | SFEBES2016

Male puberty and spermatic development

Davies Kate

This session will focus on spermatogenesis and pubertal development in boys, emphasizing the use of the Tanner staging system in clinical practice. Implications of early and delayed puberty will be discussed, plus normal pubertal development, and its relevance in sperm banking for children undergoing cancer treatment....

ea0027s33 | Endocrine Nurse Session | BSPED2011

Hows, whys and wherefores o endocrine testing: nurse perspective

Davies K

It will focus on nursing issues relevant in today’s practice, by predominantly centering on the ‘Endocrine Testing’ section of the competency framework, by exploring the Competent, Experienced and Senior / Expert Practitioner roles with reference to how to carry out dynamic endocrine function tests. Other topics will also be touched upon in order to initiate a discussion amongst all the nurses present, such as consent, information leaflets and other practicaliti...

ea0017s5 | (1) | BSPED2008

Body composition in survivors of childhood malignancy

Davies JH

It has been estimated that by 2010 more than 1 in 600 adults will be survivors of childhood cancer. Multi-agent chemotherapy regimens, targeted and fractionated radiotherapy and individualised protocols to match disease stage, have all contributed to improved outcome. The greater numbers of survivors have focussed concerns on the associated long-term morbidity from cancer treatment and/or the previous malignant disease process itself. Although follow-up of survivors into adult...