Searchable abstracts of presentations at key conferences in endocrinology

ea0044p17 | Adrenal and Steroids | SFEBES2016

The effect of time of day and utility of 30 and 60 min values in 250 μg ACTH stimulation test

Munro Vicki , Elnenaei Manal , Doucette Steve , Kaiser Stephanie , Ali Imran Syed

Background: Despite the widespread use of the 250-μg Cosyntropin test (ACTH test) for the diagnosis of adrenal insufficiency (AI), the effect of timing of the test on 30- vs. 60-min serum cortisol values remains unclear. Also, there is limited evidence comparing the value of performing both 30- and 60-min cortisol levels.Methods: We conducted a retrospective cohort study of all ACTH tests conducted at the Halifax Neuropituitary Program, Nova Scotia,...

ea0065p276 | Neuroendocrinology | SFEBES2019

The effect of tumor staining pattern on secondary hormonal deficiency in nonfunctioning pituitary adenomas

Ali Imran Syed , Almistehi Wael M , Hebb Andrea L O , Doucette Steve , Tramble Lisa , Massoud Emad , Clarke David B

Secondary hormonal deficiency (SHD) is common in patients presenting with nonfunctioning pituitary adenomas (NFA). NFA can either stain for various hormones or be non-hormone staining on immunocytochemistry. To date, no study has assessed the association between staining pattern of NFA and pattern of SHD at presentation. The Halifax Neuropituitary Program has been prospectively collecting comprehensive data on all neuropituitary patients in the province of Nova Scotia, Canada ...

ea0011p270 | Diabetes, metabolism and cardiovascular | ECE2006

Hormonal profile associated with the insulin sensitive obese subjects

St-Pierre D.H. , Karelis A.K. , Henry J.F. , Malita F.M. , Fontaine J. , Mignault D. , Brochu M. , Bastard J.P. , Doucet E. , Cianflone K. , Rabasa-Lhoret R.

Recently, several groups have described a subset of obese women, who despite having excessive total body fat, are insulin sensitive (ISO for Insulin Sensitive Obese), normotensive and present a favorable lipid profile. Adiponectin, ghrelin and leptin play important roles in the regulation of energy metabolism and food intake. Moreover, all three hormones have been reported to be closely linked to insulin resistance and regulated by insulin. Therefore, we propose to investigate...