Endocrine Abstracts

The conversion of Hashimoto thyroiditis (HT) to hypothyroidism is frequently observed in daily clinical practice, but the development of Grave’s disease (GD) after long-standing hypothyroidism is rare and intriguing. A 70-year-old woman visited an endocrinologist, complaining of increased heart rate, anxiety, and a feeling of discomfort in the neck. Past medical history revealed HT with hypothyroidism. Laboratory tests showed significantly increased thyroid-stimulating ho...

Background: World Health Organization (WHO), United Nations International Children’s Emergency Fund (UNICEF), and the International Council for Control of Iodine Deficiency Disorders included neonatal thyroid stimulating hormone (nTSH) as one of the indicators for assessing iodine deficiency at a population level and as a monitoring tool in programs of iodine supplementation. A prevalence of nTSH concentrations in dry blood spots (DBS) above 5 mlU/l below 3% has been prop...

Background: Congenital hypothyroidism (CH) is one of the most common preventable causes of mental retardation and intellectual disability. The overall incidence of CH ranges from 1 in 3,000 to 1 in 4,000 live births, with variation worldwide among different ethnicity [1]. During the period 1993–2000 the incidence of CH in Lithuanian population was estimated as 1 in 4800 live births [2]. The aim of present study was to determine the incidence of CH among new-borns in Lithu...

Iodine deficiency is the main cause of preventable mental retardation in children. Urinary iodine excretion is a marker of recent iodine intake and is used to monitor the iodine status of population. Iodine excretion in Lithuanian schoolchildren was previously investigated in 2001. The main objective of this study was to evaluate iodine excretion in children, ages 6–12, living in Vilnius, Lithuania.MethodsUrine samples were co...