Searchable abstracts of presentations at key conferences in endocrinology

ea0011p343 | Diabetes, metabolism and cardiovascular | ECE2006

Obesity and expression of serotonin transporter (SERT) in human platelets

Marsili A , Santini F , Pelosini C , Betti L , Fabbrini L , Galli G , Ricco I , Baroni S , Italiani P , Fierabracci P , Giannaccini G , Pinchera A

Serotonergic transmission is involved in eating behaviour and body weight control. Comparison of SERT properties in blood platelets and serotonergic synaptosomes suggests that the human platelet can serve as an appropriate model for the transport, metabolism and release of serotonin by serotonergic neurons.Aim of this study was to evaluate SERT expression in platelets obtained from overweight or obese subjects (OB) as compared with normal weight healthy volunteers (C), and to ...