Endocrine Abstracts

Introduction: Primary hyperparathyroidism (HPT) is usually observed in old people. It is very rare in children and young adults. Our aim is to analyze clinical, biological aspects, and outcome in six subjects under 30.Methods: The six subjects were chosen among 36 people hospitalized for primary HPT from 2009 to 2012. All had clinical examination, routine analyses, biological (blood and urinary calcium and phosphorus, and vitamin D) and hormonal (at leas...

Diet and physical activity are éssensiels in support of diabetes mellitus (DM) as well as medical treatment.Aim: Evaluate the results of diet and physical activity on anthropometric and metabolic parameters of T2DM patients untreated population and methodology. 30 newly diagnosed T2DM patients (20W and 10 M; mean age 56.23±0.96 years were placed under hygienodietetic rules. Each patient underwent a clinical examination specifying TT, BMI, and m...

Introduction: Abnormalities of midline (AML) can be isolated or to be associated to secretory pituitary abnormalities that reflect a developmental defect of the hypothalamic pituitary (HP) region.Aim: Find AML in GH deficiency (GHD) and see their relationship with the appearance of the HP region and the severity of hypopituitarism (I P).Population and methodology: 160 children (141 ♂, ♀ 19) (IGH) underwent a clinical ex...

Studies showed an increase of cardiovascular risk (CVR) and reduction of the life expectancy observed in the anterior pituitary insufficiency (API) subjects. The morbimortality would be related to GH deficiency not substituted.Aim: To seek the frequency of the hypertension and analyse the predictive factors in subjects with API.A retrospective study relating 55 (47 women, eight men) subjects with API: interrupted pituitarystalk n:6...

Subclinical hypothyroidism (SCH) represents a mild or compensated form of primary hypothyroidism. Although the relationship between SH and lipid profile have been reported in several studies, the results are conflicting. The objective of the present study is to assess dyslipidemia among patients with SCH. Our study included 107 patients vs 108 sex matched controls. Clinical information and medical history were obtained through a questionnary from all SCH patients and normal co...

Several observations brought reported a big frequency (12–50%) of pituitary insufficiency and abnormalities of the median line. The endocrine disorders are hypothamic origin and come along of pituitary ontogeny in more 30% of the cases. These abnormalities are associated with a defect of the embryological development of the bird nasofrontal which allows the development of various regions of the encephalon and the face. We report the observations of two boys KY 18 years ol...

IGF1 represent an important key player in several physiologic process, so it can be implicated in different pathologies among delays of growth. A comparative study was realized comparing a group of healthy Algerian children of normal size (n: 266) and a group presenting a GH deficiency (GHD n: 107)to a group of healthy westerners children of normal size(Serie of ROSENFIELD).The results are as follows: Before the age of 04 years, there is a ...

The recourse to the imagery by magnetic resonance brings to discover pathological images requiring an adapted exploration and therapeutic. The thickening of the pituitary stem can raise diagnostic difficulties. We report the case of 06 patients: 02 men and 04 women, average age is 31 years (04 years 1/2 at 48 years).The consultation is justified by an insipid diabetes in 05 cases, an amenorrhea - galactorrhea in a case. The hormonal assessment revealed a...

IntroductionMarfan syndrome is a rare autosomal dominant genetic disease resulting from a mutation in the gene encoding type 1 fibrillin (FBN1), which is a glycoprotein in the composition of elastic fibers in connective tissue. It mainly affects the cardiovascular, musculoskeletal and ocular systems.Case presentationWe report the case of a 14-year-old girl, with no particular history, referred to an endocrino...

Introduction: The causes of short stature are various and their frequency depends on whether we consult in pediatric or endocrinology.Although endocrine pathology is involved in a little <10% of cases, its recognition is important because it leads to a specific treatment that enhances the stature prognosis.Aim: Search etiologies statural delays observed in endocrinology and assess the frequency of GH deficiency.<p class="ab...