Endocrine Abstracts

Sertoli cells are the most active cell population in the prepubertal testis. During infancy and childhood, male hypogonadism can be evidenced by assessing Sertoli cell function without the need for stimulation tests. Anti-Müllerian hormone (AMH) is a distinctive serum marker of the prepubertal Sertoli cell, which is high from foetal life until puberty. AMH production is stimulated by FSH and potently inhibited by androgens. Initially used only to distinguish between patie...