Endocrine Abstracts

Introduction: The prevalence of diabetes mellitus (DM) in patients with coronavirus disease (COVID)-19 varies widely, depending on population characteristics, country, age and disease severity. Moreover, pre-existing DM seems to double the risk of both critical COVID-19 and mortality.Aim: To evaluate incidence and mortality risk of COVID-19 in a large diabetic population in Northern Italy.Methods: A retrospective, observational, bi...

Background: QT interval reflects cardiac ventricular repolarization and, if prolonged, increases the risk of malignant arrhythmias such as torsade de pointes. QT interval duration is similar in boys and girls during childhood but shortens in males after puberty. In fact, reference limits for QTc in adults reflect this difference, i.e. lower than 460 ms in women and lower than 440 ms in men. Experimental studies suggest that testosterone is the major contributor to shortening o...

Eating disorders are less common in men than in women. Furthermore, in males, a restrictive eating behaviour is frequently secondary to other psychiatric disorders. In case of suspected primary anorexia nervosa (AN), in male patients it is obviously impossible to rely on a typical clinical sign as is amenorrhea.Case description: A 23-yr old man came to our observation because of an important weight loss in the last two years (from 60 to 48 kg, body mass ...

Background: Diabetes mellitus (DM) prevalence in patients with severe acute respiratory coronavirus virus (SARS-CoV-2) infection differs among studies, although pre-existing DM seems to double the risk of critical infection and mortality.Objectives: To evaluate incidence and mortality risk of SARS-CoV-2 infection in a large diabetic population in Northern Italy in pre-vaccine era.Methods: Retrospective, observational, big data stud...

The diagnostic approach to GH deficiency (GHD) in obese patients is complicated by the reduced spontaneous and stimulated GH secretion associated with overweight. A GH response to GHRH+arginine lower than 4.2 μg/l is currently considered indicative of GHD in obesity (Corneli et al., Eur J Endocrinol 2005). Aim of the study was to verify the diagnostic validity of this cut-off value by investigating the effect of acute pharmacological blockade of lipolysis on...