Searchable abstracts of presentations at key conferences in endocrinology

ea0013p265 | Reproduction | SFEBES2007

Expression of the IGF system in the involuting bovine uterus

Llewellyn Samantha , Fitzpatrick Richard , Murphy John , Wathes Claire

Uterine involution is a critical component of postpartum reproduction, which involves endometrial tissue repair, myometrial contraction and bacterial clearance. The uterus synthesises insulin-like growth factors (IGF-I and –II), IGF-I receptor (IGF-1R), and IGF binding proteins (IGFBPs -1 to -6) that regulate IGF bioavailability. This study used tissue from 12 multiparous Holstein-Friesian cows at day 14 postpartum to investigate expression of the uterine IGF system durin...

ea0007p299 | Clinical case reports | BES2004

Human chorionic gonadotrophin responsive adrenal cortical carcinoma and Cushing's Syndrome in pregnancy

Hoashi S , O'Connell J , Kelly S , Young L , Fitzpatrick J , O'Keane C , Kinsley B

A 28 years old lady presented at 21 weeks gestation with bipedal oedema and 4 week history of easy bruising and weakness and aching of the thighs. She had no significant past medical history and had prior uneventful pregnancy 17 months previously. On examination she was hypertensive (180/100 mmHg), had puffy face, prominent abdominal striae and bilateral leg oedema. Serum potassium was 2.6 mmol/l and random plasma glucose was 8.6 mmol/l. OGTT confirmed gestational diabetes and...

ea0065p13 | Adrenal and Cardiovascular | SFEBES2019

Seasonal vaccination and associated steroid management practice in adrenal insufficiency

O'Murchadha Liam , Dib Liana , Hannon Anne Marie , Dineen Rosemary , Garrahy Aoife , Thompson CJ , Fitzpatrick Fidelma , Sherlock Mark

Background: Adrenal insufficiency remains a potentially life-threatening condition, necessitating adequate glucocorticoid replacement and appropriate stress-related adjustment to avoid crisis. Flu-like illness is a key precipitant of adrenal crisis. While some authorities recommend annual influenza vaccination for such patients, uptake rates in this population are unknown. Additionally, while seasonal vaccines may lead to minor symptoms in the general population, there are no ...

ea0024p3 | (1) | BSPED2010

Pseudohypoaldosteronism Type 1 in Infants: A UK Experience

Amin N L , Barth J H , Field H P , Frazer S , Finlay E , Tyerman K , Feather S , Fitzpatrick M , Saville G , Alvi S , Mushtaq T

Background: Type 1 pseudohypoaldosteronism (PHA) is characterised by resistance to aldosterone action, resulting in salt wasting, hyperkalaemia and metabolic acidosis in the neonatal period. Type 1 PHA can be classified as Renal PHA (autosomal dominant (AD)), and the more severe Multiple target organ defect / systemic PHA (autosomal recessive (AR)). The aim of this study was to ascertain the incidence of PHA, and characterise mode of presentation, management and clinical outco...