Searchable abstracts of presentations at key conferences in endocrinology

ea0043oc31 | Meta-Analysis of Phase 2/3 Studies | WCTD2016

Do mobile phone applications improve glycemic control in the self-management of diabetes: A systematic review, meta-analysis and GRADE of 14 RCTs

Carter Ben , Hou Can , Hewitt Jonathon , Francisa Trevor , Mayor Sharon

Background: Diabetes mobile phone applications (hereafter referred to as diabetes apps) are a promising tool for self-management. Due to the ubiquitous, low cost, interactive and dynamic health promotion, and there is potential for a cost-effective intervention in diabetes self-care. However, there is uncertainty of the clinical effectiveness.Objectives: To investigate the effect of mobile phone applications on glycemic control in the self -management of...

ea0032p357 | Diabetes | ECE2013

Acute exercise leads to increased HbA1c and fructosamine levels in athletes with type 1 diabetes

Forga Luis , Goni Maria Jose , Chinchurreta Laura , Lafita Franciso Javier , Iriarte Ana , Manuel Fernandez- Real Jose

Introduction: In patients with type 1 diabetes, exercise has not consistently been shown to improve glycemic control, as measured using HbA1c levels. Participation in competitive sports may even worsen glycaemic control. Free radicals and oxidative stress markers are known to increase during acute exercise in parallel to decreased circulating antioxidant concentrations. We aimed to analyze the effects of chronic and acute exercise on circulating HbA1c and fructosamine levels.<...

ea0009s51 | Skeletal health | BES2005

Steroids and the skeleton

Francis R

Steroid hormones play an important role in the skeleton and may be involved in the pathogenesis and management of osteoporosis. The decline in estrogen levels at the menopause is associated with increased bone resorption and accelerated bone loss. Although there is no comparable reduction in serum testosterone in middle-aged men, the gradual decline in free testosterone may contribute to bone loss with age. Hypogonadism is a well-established cause of secondary osteoporosis in ...

ea0020p608 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

GH resistance in a group of chronic fatigue syndrome patients

Coucke Francis , Dockx Yanina

Objective: The rule of GH and IGF1 in the pathogenic of CFS is unclear. One study (related articles number 2) found no difference in IFG1 levels between controls and patients. However in fibromyalgia there are reports of subgroups of patients with a low IGF1 and normal to high GH. This phenomenon is also known with anorexia nervosa patients due to the malnutrition.Method: We selected a group of ambulatory CFS patients fulfilling the Fukuda criteria with ...

ea0078cme2.1 | Session 2 | BSPED2021

Update in the Recognition & Management of Adolescent PCOS

Ibanez Lourdes , de Zegher Francis

Polycystic ovary syndrome is the most common cause of hirsutism & menstrual irregularity in adolescent girls. It is often accompanied by obesity and insulin resistance and associated to lifelong co-morbidities including reduced fertility, type 2 diabetes, premenopausal cancer, depression, and pregnancy and offspring complications. There is no approved therapy for PCOS in adolescent girls. Oral contraceptives (OCs) are prescribed off-label to approximately 98% of young PCOS...

ea0065p107 | Bone and calcium | SFEBES2019

Not all cases of hypercalcemia with calcium above 3.0 mmol/l and raised parathyroid hormone levels are due to primary hyperparathyroidism

Francis-Emmanuel Patrice , Tauni Rahat

Parathyroid hormone-dependent hypercalcaemia is one of the commonest conditions seen in endocrinology clinics. Primary hyperparathyroidism (PHPT) is the usual cause although some cases are due to other conditions including familial hypocalciuric hypercalcaemia (FHH). Making the distinction between PHPT and FHH is important in order to avoid unnecessary parathyroid surgery. Urinary calcium quantification is an integral part of diagnostic investigations. We present the case of a...

ea0067gp38 | Poster Presentations | EYES2019

Management of (severe) primary hyperparathyroidism in pregnancy

Tauni Rahat , Francis-Emmanuel Patrice

: Primary hyperparathyroidism (PHPT) is a common endocrine condition but is relatively rare in very young people and during pregnancy. The diagnosis in pregnancy poses a unique challenge and is often missed as the symptoms of hypercalcemia mimic those in pregnancy. We present the case of a 20-year old woman who was found to have severe hypercalcemia after she had persistent vomiting in early pregnancy. Biochemistry revealed adjusted calcium of 5.34 mmol/L, parathormone of 103....

ea0065p103 | Bone and calcium | SFEBES2019

A case of severe hypercalcemia detected in early pregnancy

Francis-Emmanuel Patrice , Wijenaike Nishan , Tauni Rahat

Primary hyperparathyroidism (PHPT) is a common endocrine condition. Outside of syndromic presentations, it is relatively rare in young people and during pregnancy. The diagnosis in pregnancy poses a unique challenge and is often missed as the symptoms of hypercalcemia mimic those in pregnancy. We present a case of a 20-year old woman who was found to have severe hypercalcemia after she had persistent vomiting in early pregnancy. Biochemistry showed adjusted calcium of 5.34 mmo...

ea0039ep6 | Adrenal | BSPED2015

Not always CAH: urine steroid profiling in the investigation and diagnosis of adrenal causes of neonatal hyponatraemia and failure to thrive

Lam Francis , Matei Cristina , Rumsby Gill

A 1 month old baby boy presented at a local district general hospital with failure to thrive. He was born to non-consanguineous Eastern European parents, with an 18 month old healthy sister. The term birth was unremarkable, with nil of note from the antenatal history. Initial clinical examination revealed a slightly low but stable blood pressure for age, but was otherwise normal.Investigations: Biochemistry results showed low plasma sodium (125 mmol/l) a...

ea0037ep114 | Steroids, development and paediatric endocrinology | ECE2015

Salt and puberty: self-regulated salt intake and the effect of salt on puberty

Pitynski Dori , Flynn Francis , Skinner Donal

The onset of puberty is changing in western countries. Puberty is the activation of the reproductive system, and is initiated by a complex series of events that are not fully understood. BMI has been linked to the advancement of puberty, but is unlikely to be the whole story as girls with a normal BMI are also advancing through puberty earlier. It is well known that western diets are high in calories, but the high salt content in these diets has been overlooked as a potential ...