Endocrine Abstracts

Aim: Shortage of tetracosactide in the UK has put pressure on clinicians to reduce the number of SST’s ordered. Our aim was to establish if a lower baseline cortisol level from the currently accepted cut-off could predict a positive SST outcome. This would aid our Endocrine Department in rationalising use of tetracosactide.Methods: A retrospective observational study of indications and results of SST’s performed in non-critically ill general me...

We report a case of a 51 year-old gentleman with increased serum creatine kinase (CK) due to hypocalcaemic tetany caused by idiopathic hypoparathyrodism. Raised CK (1738 u/L) was incidentally noted in this patient by his GP. He had ongoing symptoms of hypocalcaemia with intermittent tetanic spasms in his hands and scalp and easy fatigability for 2 years. His examination showed normal stature, no evidence of myopathy with normal deep tendon reflexes, Trousseau’s sign was p...

Androgen secreting ovarian tumours account for 0.1% of ovarian tumours. They can appear at any age (mean, 42 years) and can be slow growing.We report a case of androgen secreting ovarian tumour diagnosed at a delayed stage. It is unusual as it evaded diagnosis because of various factors, which we believe should be learning lesions.A 56-year-old lady with medical history of sub-arachnoid haemorrhage (SAH), presented with features of...

A 67-year-old lady presented with hypoglycaemic coma, treated with dextrose infusion. Previously she had a 3-month history of weight gain with increasingly frequent episodes of shaking and blurred vision, particularly at night, relieved by food.A 72-hour fast was undertaken. Within 2 h, she became confused. Serum glucose was 1.1 mmol/l with serum insulin 527 pmol/l (0–60 pmol/l), proinsulin 320 pmol/l (0–7 pmol/l) and C-peptide 2991 pmol/l (174...