Searchable abstracts of presentations at key conferences in endocrinology

ea0011s60 | Steroid hormone receptors | ECE2006

Cell membrane receptors of steroid hormones

Brosens J , Huhtaniemi I , Gellersen B

Rapid activation of diverse signal transduction pathways is thought to play an integral role in the cellular responses to many steroid hormones, including progesterone. This sex steroid is essential for normal reproduction in nearly all species. The recent cloning of a G-protein coupled receptor with the properties of a membrane progestin receptor (mPR) in fish and the subsequent identification of three mammalian homologues (mPR-alpha, -beta, and -gamma) raised the possibility...