Searchable abstracts of presentations at key conferences in endocrinology

ea0011oc38 | Neuroendocrinology and neoplasia | ECE2006

Germline mutations in patients with apparently sporadic pheochromocytomas/paragangliomas

Mannelli M , Gaglianò MS , Simi L , Ercolino T , Becherini L , Pinzani P , Sestini R , Bernini GP , Mascalchi M , Genuardi M

Paragangliomas (PGLs) and pheochromocytomas (PHEOs) are neural crest-derived tumors (NCD). PGLs can be localized in parasympathetic ganglia (in the head-neck region or in the anterior thorax) or in sympathetic ganglia (in the posterior thorax or in the abdomen). PHEOs can be considered PGLs arising in the adrenal gland.NCD tumors can present as sporadic or familial. The percentage of hereditary forms is supposed to be 25%. The susceptibility genes predis...

ea0011p515 | Endocrine tumours and neoplasia | ECE2006

Different scintigraphic patterns between sympathetic and parasympathetic paragangliomas

Gaglianò MS , Simi L , Ercolino T , Becherini L , Sestini R , Mascalchi M , Genuardi M , Briganti V , La Cava G , Olianti C , Mannelli M

Paragangliomas (PGLs) are neuroendocrine tumors arising from the neural crest and localized from the skull base to the pelvic floor. In particular, parasympathetic PGLs arise in the head/neck region (carotid body, vagal nerve, jugulare and tympanic glomus) and more rarely in the anterior thorax, while sympathetic PGLs are localized in the posterior thorax and in the abdomen and secrete catecholamines.Localization of paragangliomas might be performed by a...