Endocrine Abstracts

To date, studies focusing on long-term cardiovascular risk (CVR) of polycystic ovary syndrome (PCOS) women are not available, as well as longitudinal data regarding the endothelial structure and function.The aim of this observational study was to examine both endothelial structure and function in young women with PCOS at 5-year follow-up.Thirty PCOS women (age 22.2±2.5 years, mean±S.D.; BMI 22.4±2.1, k...

Clomiphene citrate (CC) is the first-line therapy for inducing ovulation in infertile women with polycystic ovary syndrome (PCOS), but about 20% of them results un-responsive. Lifestyle modification programs are effective in restoring ovarian function and improving reproductive outcomes in PCOS patients.The aim of the present randomized controlled trial was to test the hypothesis that a very short-term intervention consisting in structured exercise train...

Introduction and Aim: Polycystic Ovary Syndrome (PCOS) is an endocrine disease closely related to several risk factors for cardiovascular disease. Previous study demonstrated an impaired cardiopulmonary functional capacity in PCOS women. The present study was performed to evaluate the effects of 3-months exercise training (ET) programme on cardiopulmonary functional capacity in young women with PCOS.Patients and Methods: The study was conducted according...

Introduction and aim: Polycystic Ovary Syndrome (PCOS) is a common disorder associated with a wide range of endocrine and metabolic abnormalities. Obesity is present in about 45–50% of PCOS women. Increased cardiovascular risk factors and evidence of subclinical cardiovascular disease (CVD) have been reported in PCOS. The aim of the present study was to evaluate whether visceral fat amount may be considered as predictor for early CVD in PCOS women.P...

Introduction and aim: Polycystic ovary syndrome (PCOS) is associated with an adverse metabolic and cardiovascular risk (CVR) profile, including: diabetes, insulin resistance, dyslipidemia and hypertension. Heart rate recovery (HRR) is a measure of autonomic dysfunction and an abnormal HRR is also associated with increased mortality. To date, no evaluation of autonomic function in young PCOS women has been performed, therefore the aim of the present study was to evaluate the HR...

The polycystic ovary syndrome (PCOS) is not only the first cause of female infertility but also a complex, endocrine, multifaceted disease with important health implications. PCOS is often associated to the metabolic syndrome, and insulin resistance represents the main characteristics for both these syndromes. The metabolic disturbances characteristic of insulin-resistant states have been linked to the role of mitochondrial function and in particular to the maximal oxygen cons...