Endocrine Abstracts

Introduction: There are few studies either hospital bases or population based in Africa and in Angola we also have the same situation regarding endocrinology data. With this paper, the Angolan Society of Endocrinology Diabetes and Metabolism (SAEDM), wants to contribute to the systematic and continued study of endocrine pathology in Angola.Objective: Study of the casuistic of endocrine pathology in ambulatory setting regarding the year 2015.<p class=...

Introduction: The treatment with tyrosine-kinase inhibitor drugs (1st line Lenvatinib) in patients with radioiodine-refractory differentiated thyroid cancer (I-131) and disease progression can be burdened by important side effects which often require suspension/reduction of the therapy and correct multidisciplinary management.Patients and methods: Clinical/histopathological characteristics, outcome, adverse events and the role of gender have been evaluat...

Women with CAH have decreased fertility and sexual activity because of psychological aspects and genital status. The aim of this study was to evaluate sexual function and psychological attitudes in 18 women with CAH due to 21-HD (12 with non-classical, four with salt-wasting and two with simple virilizing CAH; 20–48 yrs) under standard treatment, and 18 age-matched healthy women. Sexual function was evaluated by a validated Female Sexual Function Index (FSFI) questionnair...

Introduction: The reactivation of autoimmune disorders has been described in patients with hypercortisolism after normalization of cortisol secretion. This phenomenon is probably related to the loss of immunosuppressive effect of endogenous glucocorticoids. This is a report of two patients with Takayasu arteritis (TA) and Cushing’s disease (CD), a novel association never described in literature, in whom TA was exacerbated after normalization of cortisol secretion.<p c...

Literature evidenced correlation between psychiatric disorders and overweight/obese (BMI>25) conditions, management and treatment. There are involved psychiatric diseases and temperamental traits. Our study, born from collaboration between Psychiatric and Plastic Surgery Clinic of Padua University, wants to detect psychiatric disorders, temperamental traits and body image perception in overweight-obese patients who seek surgical liposuction or abdominoplastic. We studied (...

Cabergoline (CAB) and other dopamine agonists are usually discontinued shortly after hyperprolactinemic patients become pregnant. Data on maternal and foetal exposure to CAB and on recurrence of hyperprolactinemia after pregnancy are still limited. The current survey study aimed at elucidating the safety of exposure to CAB during early pregnancy and the recurrence rate of hyperprolactinemia after pregnancy. Thus, 68 pregnancies in a cohort of 59 patients with hyperprolactinemi...

Background: Hypogonadism is a clinical entity characterized by low serum testosterone (T) levels associated with several clinical signs and symptoms which can negatively affect the quality of life. T replacement therapy (TRT), restoring serum T concentrations, improves signs and symptoms related to hypogonadism. Many T formulations are presently available. The aim of the study was to assess effects of 2% gel TRT on serum T concentrations, erectile function, muscle strength and...

Objective: The impact of first-line somatostatin analogues (SSA) on glucose tolerance in acromegaly was investigated during a 10 year period.Patients: One hundred and twelve patients treated with depot SSA.Outcome measures: Primary outcome measures were fasting glucose levels. Data were analyzed according with baseline glucose tolerance and disease control.Results after 12 months SSA treatment: In the 63 pati...

Serum CT is the most specific marker of Medullary Thyroid carcinoma (MTC). Although Pg test is the most frequently used to induce CT secretion, the poor availability of Pg makes it necessary to look for different agents. Aim of this work was to compare the induction of CT secretion following 2 different stimuli in the same patient. We studied 25 patients (14 females, 11 males; mean age 50±15 yrs; range 12–77 yrs). All patients were subjected to both tests by injectio...

Introduction: Acromegaly is a systemic disease frequently characterized by hypogonadotropic hypogonadism, endothelial dysfunction and diseases classically associated with an increased incidence of erectile dysfunction (ED) (hypertension, dyslipidemia, impaired glucose metabolism) and premature ejaculation (prostatic disease). Furthermore, the high prevalence of ED may negatively affect ejaculatory function. The purpose of this study was to evaluate the ejaculatory function of ...