Endocrine Abstracts

Background: The aim of this report is to describe a fortuitely discovered association between parathyromatosis and occult sclerosing papillary carcinoma of the thyroid.Case description: A 56-year-old woman presented with pyelic relapsed stone, bone pains and iPTH=348 ng but normal calcemia as manifestations of recurrent primary hyperparathyroidism after a right inferior parathyroid adenoma resection done elsewere 6 years ago Sonography showed a 5 mm hypo...

Introduction: Intraoperative quick PTH (iqPTH) monitoring is important in the treatment of primary hyperparathyroidism (pHPTH), allowing, together with preoperative localisation, the switch from routine bilateral neck exploration to limited gland excision.Aims: We checked the advantage of iqPTH for improving the cure rate of patients operated for pHPTH by using minimally invasive surgery (MIS).Materials and methods: Retrospective s...

Carcinoma showing thymus-like differentiation (CASTLE) is a rare malignancy, localized in the thyroid parenchyma. As far as we know, only a few CASTLE cases are described in literature. The diagnosis is based on immunoreactivity, the main characteristic is positivity to CD5, which reveals a thymic differentiation. We report the case of a 63-years-old male, who presented with a 3 cm solid, hypoechoic nodule in the lower part of the left thyroid lobe, with underlying structures ...

Introduction: The significant increase in the average lifespan of the general population lead to a proportional enhancement in the prevalence of benign and malignant thyroid conditions and equally the number of surgeries for this pathology.Patients and method: In a personal series of 464 thyroid disorders undergoing surgery over two decades we recorded 51 patients (21.5%) aged over 65 years of which 11 (2.4%) having over 75 years. Demographic, clinical a...

Background: Chronic inflammatory processes of the thyroid represents an important proportion of the gland’s pathology but the majority of them must be treated by nonsurgical methods, thyroidectomy remaining circumstantially indicated.Patients and methods: In 14 cases (3%) from 464 operations for different thyroid lesions lesions we have encountered authentic inflammatory processes in nine cases of Hashimoto’s thyroiditis (two associated with pa...

Introduction: Pheochromocytoma occasionally associates with pathological lesions of the adrenal cortex. We report a case of non-functional adrenocortical nodular hyperplasia with a concomitant pheochromocytoma in the controlateral adrenal and empty sella.Case report: We describe the case of a 52 year old women with a history of essential hypertension and type 2 diabetes mellitus. She complained of: nausea, abdominal pain, vomiting and constipation. The c...

Background: The optimal surgical technique in patients with refractory renal hyperparathyroidism (RHP) on hemodialysis for end stage renal disease is still a point of debates.The high percentage of recurrences after standard surgical procedures, i.e. subtotal parathyroidectomy (SPtx) and total parathyroidectomy with autotransplantation (TPtx+At) reactualised the practice of total parathyroidectomy (TPtx).Patients and methods: Forty...

Patient DE, a 49-year-old woman, was operated in 2005 for two giant-cell tumours of the mandible, and in 2008 for another tumour with the same localisation and histology. Inferior cervical ultrasound after the second surgery revealed a parathyroid adenoma of 20×27×15 mm behind the lower pole of the right thyroid lobe, confirmed by Tc tetrofosmin scintigraphy. The patient had metabolic features suggestive for primary hyperparathyroidism: calcium – 10.9 mg/dl (nor...

Background: Renal hyperparathyroidism (RHPT) is a frequent complication of uremic patients on hemodialysis and despite various advances in medical therapy parathyroidectomy is necessary in a semnificative number of cases.Patients and methods: We reviewed our experience (first in Romania) regarding thirtyfour patients with RHPT operated on in our clinic between 1994 and 2007 evaluating the diagnosis methods, surgical indications, techniques and results to...

Papillary thyroid carcinoma is a slow growing tumor and is reputed to have an excellent prognosis. In 10–20% of cases, the presence of lymph node metastases led to diagnosis.Objective: To present a patient with enlarged lateral cervical masses, present for 10 years, that proved to be lymph nodes with metastatic thyroid papillary carcinoma.Case report: We report a case of an 26-year-old female patient with 10 years evolution of...